Fig. 4
From: Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
Leptin potentiates glycolysis in NPC cells. a and b The glucose consumption and lactate production were measured in NPC cells with gain- or loss-of-function of leptin. c The association of leptin and glycolytic molecules in GEPIA database was analyzed. d The transcriptional profiles of glycolytic molecules were examined in leptin-overexpressed and leptin-depleted NPC cell lines by QPCR. *P < 0.05, **P < 0.01, ***P < 0.001