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Table 1 Clinical characteristics of the NPC patients

From: Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis

Characteristics

N (%)/median (IQR)

Leptin

p-value

Low (n = 28)

High (n = 22)

Age

50(42–60)

54.5(45.3–61.0)

53.5(41.8–60.3)

0.615

Gender

 Female

13(26.0%)

9(32.1%)

4(18.2%)

0.264

 Male

37(74.0%)

19(67.9%)

18(81.8%)

AJCC stage

 I

8(16.0%)

8(28.6%)

0(0.0%)

 < 0.001*

 II

11(22.0%)

10(35.7%)

1(4.5%)

 III

7(14.0%)

6(21.4%)

1(4.5%)

 IV

24(48.0%)

4(14.3%)

20(90.9%)

T stage

 1

14(28.0%)

13(46.4%)

1(4.5%)

 < 0.001*

 2

17(34.0%)

13(46.4%)

4(18.2%)

 3

1(2.0%)

0(0.0%)

1(4.5%)

 4

18(36.0%)

2(7.1%)

16(72.7%)

N stage

 0

19(38.0%)

17(60.7%)

2(9.1%)

 < 0.001*

 1

12(24.0%)

3(10.7%)

9(40.9%)

 2

14(28.0%)

7(25.0%)

7(31.8%)

 3

5(10.0%)

1(3.6%)

4(18.2%)

M stage

 0

25(78.1%)

13(81.3%)

12(75.0%)

1.000

 1

7(21.9%)

3(18.8%)

4(25.0%)

T stage

 1&2

31(62.0%)

26(92.9%)

5(22.7%)

 < 0.001*

 3&4

19(38.0%)

2(7.1%)

17(77.3%)

N stage

 0

19(38.0%)

17(60.7%)

2(9.1%)

 < 0.001*

 1&2&3

31(62.0%)

11(39.3%)

20(90.9%)

AJCC stage

 I & II

19(38.0%)

18(64.3%)

1(4.5%)

 < 0.001*

 III & IV

31(62.0%)

10(35.7%)

21(95.5%)

 Pre-RTO BMI

24.46(21.59–26.93)

24.17(19.97–27.06)

23.59(21.04–26.49)

0.749

  1. Abbreviations: NPC nasopharyngeal carcinoma, Pre-RTO BMI pre-radiotherapy body mass index
  2. *: p<0.05