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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

Fig. 7

(i) Network mapping of effects of overexpression of KIF5B and SFRP2 affecting signaling pathways in pancreatic cancer. Orange coloring indicates predicted activation while blue coloring indicates predicted inhibition. Solid and broken lines show direct and indirect relationships between the pathway members. Yellow signifies inconsistent relationship. (ii) Expression of MUC1, KIF5B and SFRP2 in low-grade PanIN, high-grade PanIN, adenocarcinoma, Liver metastases, and soft tissue metastases. MUC1 and SFRP2 were stained with DAB-HRP while KIF5B with AP-FastRed. Image magnifications are at 40X

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