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Table 1 Top 20 proteins identified to be overexpressed in co-culture condition

From: Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

Gene Symbol Description Average PSC
Abundance
Average KPC
Abundance
Average
Co-culture
Abundance
Cxcl2 C-X-C motif chemokine 2 -0.54722 -0.77428 1.321498
Mmp3 MCG9886 -0.83013 -0.48459 1.314718
Cxcl1 Growth-regulated alpha protein -0.5383 -0.77518 1.313477
Sfrp2 Secreted frizzled-related protein 2 -0.55275 -0.74882 1.301561
Kif5b Kinesin-1 heavy chain -0.68642 -0.60435 1.29077
Crip1 Cysteine-rich protein 1 -0.47614 -0.79921 1.275346
Loxl2 Lysyl oxidase homolog 2 -0.77609 -0.46652 1.242616
Eef1g Elongation factor 1-gamma -0.41052 -0.81586 1.226383
Eif5a Eukaryotic translation initiation factor 5A-1 -0.59361 -0.62604 1.219655
Slc9a3r1 Na( +)/H( +) exchange regulatory cofactor NHE-RF1 -0.6843 -0.51219 1.196483
Glg1 Golgi apparatus protein 1 -0.98063 -0.21264 1.193274
B2m Beta-2-microglobulin -1.01516 -0.16017 1.175321
Capg Capping protein (Actin filament), gelsolin-like -0.04136 -1.12458 1.165935
Impdh2 Inosine-5'-monophosphate dehydrogenase 2 -1.11283 -0.05005 1.162882
Hdgf Hepatoma-derived growth factor -1.02418 -0.12742 1.151603
Rbmxl1 RNA binding motif protein, X-linked-like-1 -0.60948 -0.53024 1.139722
Il6 Interleukin-6 -0.05663 -1.08047 1.137099
Aimp1 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 -0.44069 -0.6953 1.13599
Ccn3 Protein NOV homolog 0.04454 -1.1511 1.10656
Lgals4 Galectin-4 -0.11029 -0.97563 1.085925