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Table 1 Top 20 proteins identified to be overexpressed in co-culture condition

From: Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

Gene Symbol

Description

Average PSC

Abundance

Average KPC

Abundance

Average

Co-culture

Abundance

Cxcl2

C-X-C motif chemokine 2

-0.54722

-0.77428

1.321498

Mmp3

MCG9886

-0.83013

-0.48459

1.314718

Cxcl1

Growth-regulated alpha protein

-0.5383

-0.77518

1.313477

Sfrp2

Secreted frizzled-related protein 2

-0.55275

-0.74882

1.301561

Kif5b

Kinesin-1 heavy chain

-0.68642

-0.60435

1.29077

Crip1

Cysteine-rich protein 1

-0.47614

-0.79921

1.275346

Loxl2

Lysyl oxidase homolog 2

-0.77609

-0.46652

1.242616

Eef1g

Elongation factor 1-gamma

-0.41052

-0.81586

1.226383

Eif5a

Eukaryotic translation initiation factor 5A-1

-0.59361

-0.62604

1.219655

Slc9a3r1

Na( +)/H( +) exchange regulatory cofactor NHE-RF1

-0.6843

-0.51219

1.196483

Glg1

Golgi apparatus protein 1

-0.98063

-0.21264

1.193274

B2m

Beta-2-microglobulin

-1.01516

-0.16017

1.175321

Capg

Capping protein (Actin filament), gelsolin-like

-0.04136

-1.12458

1.165935

Impdh2

Inosine-5'-monophosphate dehydrogenase 2

-1.11283

-0.05005

1.162882

Hdgf

Hepatoma-derived growth factor

-1.02418

-0.12742

1.151603

Rbmxl1

RNA binding motif protein, X-linked-like-1

-0.60948

-0.53024

1.139722

Il6

Interleukin-6

-0.05663

-1.08047

1.137099

Aimp1

Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

-0.44069

-0.6953

1.13599

Ccn3

Protein NOV homolog

0.04454

-1.1511

1.10656

Lgals4

Galectin-4

-0.11029

-0.97563

1.085925