Table 2 CircRNAs involved in drug resistance in GC
From: Emerging roles of circular RNAs in gastric cancer metastasis and drug resistance
CircRNA | CircBase ID | Drug | Expression | Drug resistance | Targets | Refs |
|---|---|---|---|---|---|---|
circVAPA | hsa_circ_0006990 | Cisplatin | Up | Enhance | miR-125b-3p, STAT3 | [97] |
circAKT3 | hsa_circ_0000199 | Cisplatin | Up | Enhance | miR-198, PIK3R1 | [55] |
circARVCF | hsa_circ_0092330 | Cisplatin | Up | Enhance | miR-1205, FGFR1 | [98] |
circCCDC6 | hsa_circ_0001313 | Cisplatin | Up | Enhance | miR-618, BCL-2 | [99] |
circFN1 | hsa_circ_0058147 | Cisplatin | Up | Enhance | miR-182-5p | [100] |
circPVT1 | - | Cisplatin | Up | Enhance | miR-30a-5p, YAP1 | [101] |
circ_0000260 | hsa_circ_0000260 | Cisplatin | Up | Enhance | miR-129-5p, MMP11 | [102] |
circ_0032821 | hsa_circ_0032821 | Oxaliplatin | Up | Enhance | miR-515-5p, SOX9 | [103] |
circPVT1 | - | Paclitaxel | Up | Enhance | miR-124-3p, ZEB1 | [104] |
circNRIP1 | hsa_circ_0004771 | 5-fluorouracil | Up | Enhance | miR-138-5p, HIF-1α | [105] |
circDLG1 | hsa_circ_0008583 | anti-PD-1 | Up | Enhance | miR-141-3p, CXCL12 | [106] |
circCUL2 | hsa_circ_0000234 | Cisplatin | Down | Suppress | miR-142-3p, ROCK2 | [107] |
circMCTP2 | hsa_circ_0000657 | Cisplatin | Down | Suppress | miR-99a-5p, MTMR3 | [108] |
circ_0000144 | hsa_circ_0000144 | Oxaliplatin | Down | Suppress | miR-502-5p, ADAM9 | [109] |
circ_0000376 | hsa_circ_0000376 | Bupivacaine | Down | Suppress | miR-145-5p | [110] |
circ_0000520 | hsa_circ_0000520 | Herceptin | Down | Suppress | PI3K-AKT pathway | [111] |