Table 3 Clinical significance of circRNAs in GC (Cases more than 50)
From: Emerging roles of circular RNAs in gastric cancer metastasis and drug resistance
CircRNA | CircBase ID | Sample | Expression | Clinicopathologic Features | Prognosis | Refs |
|---|---|---|---|---|---|---|
circTHBS1 | hsa_circ_0034536 | Tissue | Up | Size, stage, grade, LNM | OS | [48] |
circCCDC66 | hsa_circ_0001313 | Tissue | Up | Stage, LNM | - | [49] |
circOXCT1 | hsa_circ_0004873 | Tissue | Down | Stage, LNM | OS | [51] |
circAXIN1 | hsa_circ_0005838 | Tissue | Up | Stage, grade, LNM | - | [52] |
circFGD4 | hsa_circ_0000390 | Tissue | Down | Grade, LNM | OS | [53] |
circREPS2 | hsa_circ_0139996 | Tissue | Down | Size, stage, grade | - | [54] |
circAKT3 | hsa_circ_0000199 | Tissue | Up | Size, stage, grade, chemoresistance | OS | [55] |
circ_0023409 | hsa_circ_0023409 | Tissue | Up | Size, stage, grade | OS | [56] |
ciRS-7 | hsa_circ_0001946 | Tissue | Up | Stage, LNM | OS | [57] |
circTNPO3 | hsa_circ_0001741 | Tissue, plasma | Down | Differentiation | - | [58] |
circ_100876 | hsa_circ_0023404 | Tissue | Up | Stage, LNM, BVI, LVI | DFS | [60] |
circRanGAP1 | hsa_circ_0063526 | Tissue, plasma | Up | Size, stage, LNM | OS | [62] |
circURI1 | hsa_circ_0000921 | Tissue | Up | Stage, tumor metastasis | - | [64] |
ebv-circLMP2A | - | Tissue | Up | Stage, LNM, tumor metastasis | OS, DFS | [65] |
circNRIP1 | hsa_circ_0004771 | Tissue | Up | Size, LNM | OS, DFS | [66] |
circRELL1 | hsa_circ_0001400 | Tissue, plasma | Down | Stage, LNM, differentiation | OS, DFS | [68] |
circSHKBP1 | hsa_circ_0000936 | Tissue | Up | Size, stage, vascular invasion | OS | [69] |
circMRPS35 | hsa_circ_0000384 | Tissue | Down | Size, stage, LNM | OS | [70] |
circMAPK1 | hsa_circ_0004872 | Tissue | Down | Size, stage, LNM | OS | [71] |
circUBE2Q2 | hsa_circ_0005151 | Tissue, plasma | Up | Size, lymphatic invasion | - | [73] |
circAGO2 | hsa_circ_0135889 | Tissue | Up | - | OS | [74] |
circHuR | hsa_circ_0049027 | Tissue | Down | Stage, tumor metastasis | OS | [75] |
circVAPA | hsa_circ_0006990 | Tissue | Up | - | - | [97] |
circFN1 | hsa_circ_0058147 | Tissue | Up | Stage, grade, chemoresistance | - | [100] |
circCUL2 | hsa_circ_0000234 | Tissue | Down | Stage, LNM, differentiation | OS | [107] |
circMCTP2 | hsa_circ_0000657 | Tissue | Down | Size, stage, grade, chemoresistance | OS, DFS | [108] |
circ_0110389 | hsa_circ_0110389 | Tissue | Up | Stage, differentiation | OS, DFS | [123] |
circOSBPL10 | hsa_circ_0008549 | Tissue | Up | Stage, grade | OS, DFS | [124] |
circPVT1 | - | Tissue | Up | Stage, nervous invasion | OS, DFS | [125] |