Fig. 8

Ixa + Dina treatment exhibits anti-tumor effects in vivo. A Representative images of TUNEL, Ki67, and c-Jun immunohistochemical staining in PDX1 and PDX11 tumors after drug treatment. Scale bar = 50 μm. B - D Corresponding quantification of TUNEL (B), Ki67 (C), and c-Jun (D) expression in HCC PDX tumors. Data presented as mean ± SEM, n ≥ 80 fields. **, P < 0.01; ***, P < 0.001 compared to Ixa + Dina group. All statistical analyses were performed using two-tailed Student’s t test