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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Proteotranscriptomics of ocular adnexal B-cell lymphoma reveals an oncogenic role of alternative splicing and identifies a diagnostic marker

Fig. 1

Proteotranscriptomic characteristics of OABL. A Sampling workflow of transcriptomic and proteomic cohort. B Scatterplot of differentially expressed genes (DEGs) of 3639 protein-mRNA pairs identified in the transcriptomic cohort (31 OABLs and 17 controls) and the proteomic cohort (39 OABLs and 26 controls) between OABLs and controls. The horizontal line is at proteomic |log2(FC)| = log2(1.2); vertical line is at transcriptomic |log2(FC)| = log2(1.5). Genes with p ≥ 0.05 are labeled as black. C Bar plot of top 20 enrichment terms identified in concordant upregulated and downregulated genes. D Bubble plot of differentially enriched gene sets identified by GSEA in the transcriptomic cohort (31 OABLs and 17 controls) and the proteomic cohort (39 OABLs and 26 controls) between OABLs and controls. Gene sets with FDR < 0.2 in at least one of transcriptomic and proteomic analysis are displayed. E Bubble plot of top 15 up/down regulated gene sets identified by GSEA

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