Fig. 6

Proteomic analysis identifies DNAJC9 as a diagnostic marker of OABL. A Workflow of identifying a diagnostic marker from proteomic data. B DNAJC9 protein abundance is significantly higher in OABLs and any subtype of OABL. C ROC plot of DNAJC9, CD20, and PAX5. DNAJC9 protein abundance exhibits higher AUC than CD20 and PAX5. D Representative IF images of DNAJC9 in control and OABL samples. E MFI of DNAJC9, and overlap coefficient of DNAJC9 and DAPI are significantly higher in EMZL and DLBCL samples compared with inflammations and paracancer sites. MFI of CD20 are significantly higher in EMZL and DLBCL samples compared with paracancer sites. Each dot represents a sample. F Representative IHC images of DNAJC9 in control and OABL samples. G Staining score of bulk cells and nuclei of DNAJC9 in Inflammation, EMZL, and DLBCL samples. Each dot represents a sample