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Table 1 Correlation between ETV1 expression and clinicopathological characteristics of HCCs in two independent cohorts of human HCC tissues

From: HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET

Clinicopathological variables Tumor ETV1 expression P Value Tumor ETV1 expression P Value
Negative (n = 151) Positive (n = 109) Negative (n = 154) Positive (n = 126)
Age   52.11 51.77 0.411 50.57 51.51 0.351
(11.915) (10.417)   (10.053) (9.743)  
Sex female 31 18 0.428 19 25 0.100
male 120 91   135 101  
Serum AFP  ≤ 20 ng/ml 46 21 0.045 32 23 0.652
 > 20 ng/ml 105 88   122 103  
Virus infection HBV 108 84 0.523 119 106 0.406
HCV 14 11   11 8  
HBV + HCV 9 3   11 4  
none 20 11   13 8  
Cirrrhosis absent 40 32 0.674 42 34 1.000
present 111 77   112 92  
Child–pugh score Class A 113 83 0.884 130 103 0.630
Class B 38 26   24 23  
Tumor number single 91 63 0.703 124 86 0.026
multiple 60 46   30 40  
Maximal tumor size  ≤ 5 cm 69 39 0.126 102 56  < 0.001
 > 5 cm 82 70   52 70  
Tumor encapsulation present 95 50 0.008 118 77 0.006
absent 56 59   36 49  
Microvascular invasion absent 97 45  < 0.001 97 56 0.003
present 54 64   57 70  
Tumor differentiation I-II 131 75 0.001 132 77  < 0.001
III-IV 20 34   22 49  
TNM stage I-II 128 70  < 0.001 136 82  < 0.001
III 23 39   18 44