Fig. 4

LINC01132 potentially regulates immune-related pathways via DPP4 in HCC. A Heat map showing RNAs and proteins correlated with LINC01132 in HCC. The first column represents the correlation based on protein expression. The second and third columns represent the correlation based on RNA expression. B Scatter plots showing the correlation between LINC01132 expression and CD26 (DPP4) expression in HCC. C Biocarta pathways enriched by LINC01132-correlated genes. Pathways were ranked based on the normalized enrichment scores (NESs). Significantly positively and negatively correlated pathways were indicated in the plot. D Heatmap showing the expression and fold changes of genes after knock down of LINC01132 in HCC cell lines. E-F Enrichment plots of COMP and STEM pathways identified by genes coexpressed with LINC01132 in HCC. E for COMP pathway and F for STEM pathway. G Relative RNA expression of DPP4 in cell lines treated with knock down and overexpression of LINC01132. H Relative protein expression of DPP4 in cell lines treated with knock down and overexpression of LINC01132