Fig. 2

circ_0000098 promotes HCC cell growth and invasiveness in vitro. A, B RT-qPCR detection of circ_0000098 expression in HCC-LM3 and BEL-7404 cells transfected with the shRNA vector targeting circ_0000098 (sh-1) or control shRNA (sh-NC) (A), and in SK-Hep1 cells transfected with the circ_0000098 overexpression vector (OE) or control vector (NC) (B). C-G Clone formation assays (C), CCK-8 assays (D), migration assays (E), invasion assays (F), and flow cytometry analysis (G) were carried out in HCC cells with circ_0000098 knockdown or overexpression. *P < 0.05, **P < 0.01, ***P < 0.001