Fig. 7
FAM83H regulates PDAC progression via β-catenin. PDAC cells were treated with sh-Control, sh-FAM83H#1, sh-FAM83H#2, sh-FAM83H# 1 + β-catenin or sh-FAM83H#2 + β-catenin. A Transwell assays were conducted to assess the migration of cells in each group; scale bar: 100 μm. B Colony formation assays were performed to evaluate the proliferation of cells in each group. C The expression of effector genes of Wnt/β-catenin signaling in each group was determined by RT-qPCR. *P < 0.05, **P < 0.01 and ***P < 0.001