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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: AADAC protects colorectal cancer liver colonization from ferroptosis through SLC7A11-dependent inhibition of lipid peroxidation

Fig. 3

AADAC promotes CRC proliferation and liver colonization. A Protein expression of AADAC in sh-AADAC HCT116 cells and ADOE SW480 cells. B The proliferation ability of sh-AADAC and ADOE cells. C The colony formation ability of sh-AADAC and ADOE cells. D Representative fluorescent images and relative quantification of EdU staining in sh-AADAC and ADOE cells. E Representative images and HE staining (scale bar, 1 mm) derived from CRC liver colonization mouse model with shNC and sh-AADAC cells. F Quantification of liver colonies in (E). Data are shown as the mean ± SD. Significance was calculated by two-way ANOVA (B) and two-tailed ratio t test (C-F). p value < 0.001 (***), p value < 0.01 (**), p value < 0,05 (*), ns (not significant)

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