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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: CircPAK1 promotes the progression of hepatocellular carcinoma via modulation of YAP nucleus localization by interacting with 14-3-3ζ

Fig. 2

Characteristics of circPAK1 in HCC. A Differential expression of circPAK1 in human HCC tissues and adjacent nontumor tissues of 60 patients. B Relative expression of circPAK1 in 60 pairs of HCC tissues and matched normal tissues, shown as log2 (Tumor/Normal). C Relative expression of circPAK1 in HCC cell lines was assessed by qRT-PCR. D LM3 and Focus cells were transfected with circPAK1 shRNA (sh-circPAK1) or control shRNA (sh-NC); Hep-3B cells were infected with circPAK1 overexpression lentivirus (Lv-circPAK1) or control lentivirus (Lv-NC), the transfection efficiency was assessed by qRT-PCR. E Elevated expression of circPAK1 was negatively correlated with the overall survival (OS) and disease-free survival (DFS) of HCC patients. *p < 0.05; **p < 0.01; ***p < 0.001. Data were shown as mean ± SEM

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