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Table 1 Patient characteristics

From: Neoadjuvant toripalimab combined with gemcitabine and cisplatin in resectable locally advanced head and neck squamous cell carcinoma (NeoTGP01): An open label, single-arm, phase Ib clinical trial

Variables

Patients (N = 23)

%

Age at enrollment (years), median (range)

56 (31–70)

 

Sex

 Male

21

91.3

 Female

2

8.7

Tumor Site

 Oropharynx

3

13.0

   Root of tongue

1

4.3

   Tonsil

2

8.7

 Larynx

3

13.0

 Hypopharynx

1

4.3

 Oral Cavity

16

69.7

   Tongue

11

47.8

   Oral floor

2

8.7

   Gingiva

1

4.3

   Cheek

1

4.3

   Mandible

1

4.3

T category

 T1

1

4.3

 T2

2

8.7

 T3

8

34.8

 T4a

11

47.8

 T4b

1

4.3

N category

 N0

5

21.7

 N1

5

21.7

 N2

8

34.8

 N3

5

21.7

AJCC stage (the eighth edition)

 III

8

34.8

 IVA

12

52.2

 IVB

3

13.0

Smoking

 Never smoking

2

8.7

 No smoking for 2 years

3

13.0

 Smoking

18

78.3

HPV status (p16 expression)

 < 25%

14

60.9

 26%–75%

3

13.0

 > 75%

4

17.4

 NA

2

8.7

PD-L1 expression CPS

 < 1

1

4.3

 1 ~ 19

8

34.7

 ≥ 20

12

52.2

 NA

2

8.7

  1. Abbreviations: AJCC American Joint Committee on Cancer, HPV Human papillomavirus, PD-L1 Programmed death ligand-1, CPS Combined positive score