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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Overcoming high level adenosine-mediated immunosuppression by DZD2269, a potent and selective A2aR antagonist

Fig. 1

Ex vivo modulation of pCREB and IFN-γ in response to NECA. (A) NECA regulates CREB phosphorylation on CD3 + T cells in whole blood samples. Data from test samples from three different donors and plotted using GraphPad Prism. (B) NECA affects IFN-γ secretion in human PBMCs activated by anti-CD3/CD28 antibodies. The experiment was repeated at least 3 times, and the data shown here are from one representative experiment

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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