Fig. 2

B3GALT4 is down-regulated in NB tissues, and deficient B3GALT4 indicates a poor prognosis. A bioinformatics study was conducted to analyze the B3GALT4 expression levels in INSS stages 1 + 2 + 4 s versus 3 + 4 NB patients based on the GSE49710 (A) and GSE85047 (B) datasets. Kaplan-Meier analysis of overall survival (OS) (C, D), event-free survival (EFS) (E), and relapse-free survival (RFS) (F) using the TARGET database and GEO datasets median expression value cutoffs for B3GALT4. P-value was determined by a log-rank test. G IHC was performed to detect B3GALT4 expression in GN (n = 5) and NB (n = 25) tumor tissues (scale bars of the initial images: 100 μm, inset: scale bars of magnification: 25 μm)