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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Combined mitoxantrone and anti-TGFβ treatment with PD-1 blockade enhances antitumor immunity by remodelling the tumor immune landscape in neuroblastoma

Fig. 1

Tumor microenvironment of transplantable NB 975A2 and 9464D mouse models. A Representative flow-cytometry histograms of GD2 (blu plot), MHC class I (red plot), PD-L1 (green plot) and TGFβ expression (pink plot) in 975A2 and 9464D tumor cells. Isotype-matched negative control antibody is shown as grey plot. B-D Flow-cytometry analysis of the immune infiltrate of 50–100 mm3-size 975A2 and 9464D tumors grown subcutaneously. Levels of significance for comparison between samples were determined by ANOVA. Statistically significant P values are shown

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