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Table 1 Relevance analysis of NAT10 expression in CRC patients

From: Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA

Varible

All patients

NAT10

P value

High

Low

All Cases

80

40

40

 

Age (years)

 60

23

15

8

0.084

 ≥ 60

57

25

32

Gender

 Male

50

22

28

0.166

 Female

30

18

12

Tumor site

 Colon

35

21

14

0.115

 Rectum

45

19

26

Tumor size (cm)

 5

49

26

23

0.491

 ≥ 5

31

14

17

TNM staging system

 T1 + T2

33

13

20

0.112

 T3 + T4

47

27

20

Tumor stage

 Stage I + II

43

9

34

 < 0.001 *

 Stage III + IV

37

31

6

Lymph node metastasis

 No

46

11

35

< 0.001 *

 Yes

34

29

5

Vascular invasion

 No

61

25

36

0.004 *

 Yes

19

15

4

Nerve invasion

 No

66

30

36

0.078

 Yes

14

10

4

Distant metastasis

 No

63

27

36

0.014 *

 Yes

17

13

4

CEA (ng/ml)

 5

49

21

28

0.108

 ≥ 5

31

19

12

  1. The bold type represents P values smaller than 0.05
  2. TNM Tumour node metastasis, CEA Carcinoembryonic antige
  3. P < 0.05 was considered significant