Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA

Table 2 Relevance analysis of KIF23 expression in CRC patients

Varible	All patients	KIF23		P value
Varible	All patients	High	Low	P value
All Cases	80	40	40
Age (years)
60	23	13	10	0.459
≥ 60	57	27	30	0.459
Gender
Male	50	26	24	0.644
Female	30	14	16	0.644
Tumor site
Colon	35	23	12	0.013 ^*
Rectum	45	17	28	0.013 ^*
Tumor size (cm)
5	49	25	24	0.819
≥ 5	31	15	16	0.819
TNM staging system
T1 + T2	33	13	20	0.112
T3 + T4	47	27	20	0.112
Tumor stage
Stage I + II	43	16	27	0.014 ^*
Stage III + IV	37	24	13	0.014 ^*
Lymph node metastasis
No	46	18	28	0.024 ^*
Yes	34	22	12	0.024 ^*
Vascular invasion
No	61	28	33	0.189
Yes	19	12	7	0.189
Nerve invasion
No	66	28	38	0.003 ^*
Yes	14	12	2	0.003 ^*
Distant metastasis
No	63	28	35	0.056
Yes	17	12	5	0.056
CEA (ng/ml)
5	49	18	31	0.003 ^*
≥ 5	31	22	9	0.003 ^*

ISSN: 1756-9966