Fig. 4
From: An organoid library of salivary gland tumors reveals subtype-specific characteristics and biomarkers
PDOs recapitulate the morphologic features of parental SGTs. Representative H&E images and confocal images of IF staining with the original tissues and the corresponding organoids. Two benign tumors PA (A), BCA (B); four malignant tumors MEC (C), ACC (D), AciCC (E), SDC (F), and NSG (G); AB-PAS staining of secreted mucus in the NSG (G) and AciCC (H). Clinical diagnostic biomarkers were used to evaluate the morphological and molecular features, including Cytokeratin 5 (CK5), Cytokeratin 8 (CK8), Aquaporin 5 (AQP5), p63, C-erbB-2 (HER2), Androgen Receptor (AR), MUC4, DOG1, SOX10. Scale bar, 50 μm