Fig. 7From: Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosisA Viability of Huh7SR and 7721SR cells exposed to different concentration of orlistat as determined with the CCK-8 assay. B Combination index of sorafenib and orlistat synergistic antitumor calculated with CalcuSyn software. C and D Antitumor effects of sorafenib combined with orlistat as determined with the colony formation assay. E and F Alterations to FASN, HIF1α, and SLC7A11 protein expression levels in response to treatment with the combination of sorafenib and orlistatBack to article page