Fig. 7

Integrative functional network analysis of oxaliplatin RNA/protein fused dataset. High confidence interactions (score 0.7) showing 7 modules. Nodes in red correspond to proteins identified as differentially expressed by RNA-seq only, in blue those identified by proteomics only and in green those identified by both omics. Key for modules: 1: Glutathione metabolism & antioxidant activity; 2: Nitrogen compound metabolism; 3: Translation & tRNA aminoacylation; 4: TCA & Oxidative phosphorylation; 5: Cell cycle regulation; 6: Antigen presentation; 7: Cell adhesion