Fig. 6

The immunoregulatory effect of LPPC/MP/Ab complexes on mice. A The picture illustrated how to evaluate that the LPPC/MP/Ab complexes regulated mice splenocytes, such as cell proliferation, the cytokines expressions, and the cytotoxicity of T cells. B The MTT assay was analyzed for the effect of once or twice the modulation of LPPC/MP/Ab complexes on cell proliferation. A significant difference compared to the LPPC/MP group was indicated by * (P < 0.05, N = 9). C The cytokines secretions of the respective supernatants, such as IFN-γ and TGF-β, were evaluated by ELISA (N = 9). D The cytotoxicity of splenocytes from different mice against pCJ-HpHsp60- or pCJ-HpUreaseB-transfected BALB/3T3 cells were determined. A significant difference compared to the LPPC/MP group was indicated by * (P < 0.05, N = 9)