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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: A flexible liposomal polymer complex as a platform of specific and regulable immune regulation for individual cancer immunotherapy

Fig. 8

The immunomodulation activities of LPPC/MP complex with different antibodies. A The picture illustrated how LPPC/MP/Ab complexes could modulate the anti-tumor immunity of mice splenocytes against melanoma cells in vivo. B The number of lung nodules in mice from different treatment groups were determined. A significant difference was indicated by * (P < 0.05). C After different treatments, splenocytes were harvested from mice at the checkpoint, incubated with EGFP antigen, and the supernatants were analyzed for the expression of IFN-γ and TGF-β (*: P < 0.05, **: P < 0.01, ***: P < 0.001). D The cytotoxicity of splenocytes from different mice against B16F10-pLEGFP or B16F10 cells was determined. Statistically significant differences were compared with the LPPC/MP group (N = 6, *: P < 0.05)

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