Fig. 4

LARP6 constrain CRC invasion through ZNF267. A-D qPCR and WB were conducted to identify ZNF267 overexpression (A-B) and interference (C-D) effects. E-F Transwell migration assays in CRC cells with ZNF267-overexpression (E) or knockdown (F). Statistical results are shown in right panels (N = 3). G-H Matrigel transwell experiments illustrated the role of ZNF267 in CRC cell invasion. The right panels show the statistical results (N = 3). I With forced expression of ZNF267, matrigel transwell assays in LARP6-knockdown cells were conducted. Statistical results are shown in right panels (N = 3). *P < 0.05, **P < 0.01, ***P < 0.001, ns means no statistic difference. The error bars represent Mean ± SD