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Table 1 Clinical and pathological features of patients in ESCC microarray cohort and correlations of CCL18 expression levels

From: Integrative analysis of bulk and single-cell gene expression profiles to identify tumor-associated macrophage-derived CCL18 as a therapeutic target of esophageal squamous cell carcinoma

Clinical features

N

CCL18 expression level

P value*

Low N (%)

High N (%)

Tumor location a

 Upper

22

15 (17.6)

7 (8.3)

0.435

 Middle

39

20 (23.8)

19 (22.6)

 

 Lower

22

13 (15.5)

9 (10.7)

 

Tumor differentiation

 Well

25

14 (16.7)

11 (13.1)

0.569

 Moderate

43

23 (27.4)

20 (23.8)

 

 Poor

16

11 (13.1)

5 (6.0)

 

Pathological stage

 IA-IB

26

20 (23.8)

6 (7.1)

0.043

 IIA-IIB

29

15 (17.6)

14 (16.7)

 

 IIIA-IIIC

29

13 (15.5)

16 (19.0)

 

Tumor stage

 T1-T2

39

31 (36.9)

8 (9.5)

0.0001

 T3-T4

45

17 (20.2)

28 (33.3)

 

Nodal stage

 N = 0

48

29 (34.5)

19 (22.6)

0.484

 N > 0

36

19 (22.6)

17 (20.2)

 
  1. a exclude one patient whose tumor locate in the neck
  2. *χ2 test