Skip to main content

Table 1 Classification of common RTKs

From: Targeting IGF1R signaling enhances the sensitivity of cisplatin by inhibiting proline and arginine metabolism in oesophageal squamous cell carcinoma under hypoxia

Family

Members

EGFR

EGFR, ERBB2, ERBB3

IGFR

IGF1R

PDGFR

PDGFRα, PDGFRβ

VEGFR

VEGFR1, VEGFR2, VEGFR3

FGFR

FGFR1, FGFR2, FGFR3, FGFR4

NGFR

TRKA

HGFR

MET

EPHR

EPHA2, EPHB2

ROR

ROR1

  1. EGFR Epidermal growth factor receptor, PDGFR Platelet-derived growth factor receptor, VEGFR Vascular endothelial growth factor receptor, FGFR Fibroblast growth factor receptor, NGFR Nerve growth factor receptor, HGFR Hepatocyte growth factor receptor, EPHR Ephrin receptor, ROR Receptor orphan