Fig. 11

Guadecitabine decreases Dendritic Cells in lung TME, shifting to the subset of Lymphoid-DC. A Percentages of Dendritic Cells (CD11c+IAb+) referred to myeloid cells, not T, B, NK, myeloid (M)- (CD11c+IAb+CD11b+), and lymphoid (L)-DC (CD11c+IAb+CD11b-) referred to DC in the lung from mice receiving different treatments by flow cytometry. B percentages of L-DC/conventional DC expressing CD103 and co-expressing CD103 and CD8a in the lung from mice receiving different treatments. C serum levels expressed in pg/ml of DC cytokines in response to different in vivo treatments by Milliplex assay (n=7 mice/group). **p<0.02, ***p<0.01, ****p<0.001