Fig. 6
From: TERRA G-quadruplex stabilization as a new therapeutic strategy for multiple myeloma
GSEA performed after hit 17 treatments on the NCI-H929 cells treated with 2.5 µM of hit 17 for 24 h. Plots of significantly enriched HALLMARK gene sets: MYC_TARGETS_V1; MYC_TARGETS_V2; E2F_TARGETS; G2M_CHECKPOINT; DNA_REPAIR; OXIDATIVE_PHOSPHORYLATION. Normalized enrichment score (NES) and the corresponding p-value are reported within each graph. A p-value of zero (0.0) indicates an actual p-value of less than 0.001 (1/1000 permutations)