Table 2 Different ways of various cargos sorting to exosomes
From: Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment
Type | Subtype | Involved molecules/mechanisms | Reference |
|---|---|---|---|
MiRNA | miR-210 | nSMase2 | [173] |
MiRNA | miR-17, miR-198 | Sumoylated hnRNPA2B1 | [174] |
MiRNA | miR-486-5p | 3’ end uridylated | [175] |
MiRNA | miR-142-3p, miR-150, miR-451 | Ago2 | [176] |
MiRNA | miR-181a-5p | FUS | [99] |
MiRNA | miR-34c | Alyref | [177] |
MiRNA | miR-155 | Interaction of cRLIP and FMR1 | [178] |
LncRNA | Â | lncRNA-RBP | [179] |
CircRNA | circRHOBTB3 | SNF8 | [180] |
CircRNA | CDR1as | miR-7 | [181] |
DNA | mtDNA | endosomal pathway | [153] |
DNA | gDNA | MN | [182] |
Protein | Proteins contain the KFERQ seqence | LAMP2A | |
Protein | ECM proteins | Phosphorylated and ubiquitinated Cav1 | [185] |
Protein | Proteins with UBL structural domain | Act as PTM factors | [186] |
Protein | HSP70-mediated proteins | Endosomal microautophagy | [187] |
Metabolite | LTB4 | Lyn, fotillin-1 | [159] |