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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: ALDOC- and ENO2- driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis

Fig. 2

Transcriptomic analysis of H460 and MCF7 cell lines grown in 2D and 3D culture conditions. A Heatmap of 100 DEGs in all 3D vs 2D conditions of both cell lines. Color intensity is proportional to the magnitude of changes. Relative expression levels are shown in red (upregulation) and blue (downregulation). B GO analysis of cellular component, C biological process, and D KEGG pathway analysis of DEGs in all 3D vs 2D conditions of both cell lines. The dot size denotes the number of DEGs, while colors correspond to the adjusted p-value range

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