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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization

Fig. 3

LINC00240 enhances migration and invasion capabilities of gastric cancer cells. A In HGC-27 and MGC80-3 gastric cancer cells, LINC00240-knockdown inhibited wound-healing and the stably enforced LINC00240 expression accelerated wound-healing. The lines are the edges of cell layers. B LINC00240-knockdown reduced invasion of gastric cancer cells. Overexpression of LINC00240 promoted invasion abilities of HGC-27 and MGC80-3 cells. C Representative fluorescent images of metastatic tumors in lungs of nude mice. D Representative images of HE slides of lung metastases. E Representative images of IHC staining showing the expression of Vimentin within lung metastases. Data are shown as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001 by unpaired Student’s t test (A-F)

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