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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization

Fig. 6

LINC00240 facilitates the interaction between DDX21 and the deubiquitinase USP10. A Silencing of USP10 significantly suppressed DDX21 protein expression in gastric cancer cells. B, C Interactions between USP10 and DDX21 in gastric cancer cells were verified via Co-IP assays. D, E Silencing of LINC00240 diminished the interaction between USP10 and DDX21 in HGC-27 and MGC80-3 cells. F, G Overexpressed LINC00240 strengthened the interaction between USP10 and DDX21. H Diagram depicted how LINC00240 promotes DDX21 stabilization via intensifying interactions between DDX21 and its novel deubiquitinase USP10

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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