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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice

Fig. 3

V-aCD3Mu mediates in vitro killing of cancer cells. A Killing assays with preactivated splenocytes added in an E:T ratio of 10:1 to either 4T1, CT26, B16-F10, or TC-1 cells together with V-aCD3Mu in a twofold titration series from 200 nM and rVAR2 and aCD3Mu at 200 nM concentrations. B Killing assay with isolated T cells as effector cells. The killing assay was performed as described above using 4T1 cells. Cytotoxicity data represents data from four (4T1), two (CT26), or one (B16-F10, TC-1) experiments

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