Table 1 Genes whose loss facilitates aggressive acini growth in breast cancer
From: COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis
Genes (Kinome and Polarity library) | Number of hairpins show > 2 fold ratio enrichment |
|---|---|
DCLK1, DLG2 | 4 |
CLK2, COMMD3, EXOSC10, FRK, HUNK, MAPK9, PIP4K2B, PRPF4B, PSKH2, SGK3, TSSK1B, WNK3 | 3 |
ACR2A, ARHGEF9, BRAF, CAMKk2, CDC42BPB, CHEK1, CSNK1A1/3,DYRK1B, FPGT, HIPK4, HK2, IKBKE, IRAK1, ITGA6, LIMK3, MAP3K2/3/9, MAP4K4/5, MAPK15, MAPK3/9, MAST2, MERTK, MMP3, MYLK2, MYO3A, NBL1, NEK3/8/9, NUCKS1. PAK6, PBK, PDK1, PHKG1, PI4K2A, PIK3C2A, PIK3R1, PIP4K2B, PKN1, PRKAR2A, PRKD1, PRPF4B, PRPS2, PSKH2, RAF1, RIOK3, RIPK3, RNASEL, SGK3, SMG1, SRC, SRMS, STK11, STK40, TAB1, THP2, TLK2, TNIK, TP53RK, ULK4, WNK2, WNT16 | 2 |