Fig. 1
From: Regulation of ERα-dependent breast cancer metastasis by a miR-29a signaling
Negative correlation between miR-29a and ERα in expression in human breast cancer. A Heatmap of differentially expressed miRNAs in ERα + (MCF-7 and T47D) and ERα- (MDA-MB-231 and Hs578T) human breast cancer cell lines. B Validation of aberrant expression of miR-29a in 3 ERα- and 2 ERα + breast cancer cell lines. Data are presented as the mean ± SEM (n = 3). C Relative expression levels of miR-29a in 795 ERα + and 232 ERα- breast cancer patients from TCGA database. D Relative expression levels of miR-29a in luminal and basal-like subtypes of breast cancer from the TCGA database. E Upregulation of miR-29a in 19 TNBC breast cancer tumors in comparison to the matched adjacent tissues. F Downregulation of miR-29a in 37 luminal breast cancer tumors in comparison to the matched adjacent tissues. G Downregulation of miR-29a in 16 HER2 + breast cancer tumors in comparison to the matched adjacent tissues