Table 1 Clinical features of 34 patients enrolled in the study
Characteristics | Number (%) |
|---|---|
Age in years (Median - IQR) | 61 (54–71) |
Sex | |
Female | 20 (59) |
Male | 14 (41) |
Race | |
White | 34 (100) |
Body surface area, m2 (Median -IQR) | 1.9 (1.8–2.1) |
Performance status | |
0 | 25 (74) |
1 | 9 (26) |
2 | 0 (0) |
Primary tumor | |
Right colon | 7 (21) |
Left colon | 18 (53) |
Rectum | 9 (26) |
KRAS (N = 34), NRAS (N = 27) or BRAF (N = 31)a | |
All wild-type | 8 (24) |
Mutation | 26 (76) |
Mismatch repair | |
Proficient | 33 (97) |
Deficient | 0 (0) |
Unknown | 1 (3) |
Primary tumor removed | |
Yes | 25 (74) |
No | 9 (26) |
Number of previous regimens for metastatic disease, including rechallenge (Median - IQR) | 3 (2.25-3) |
Current extent of disease, metastatic sitesb | |
Liver | 32 (49) |
Lung | 22 (65) |
Lymph nodes | 8 (24) |
Other | 13 (38) |