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Table 5 Responses of uLMS147 Patient Derived Xenograft to PARPi and standard therapy in vivo

From: Targeting homologous recombination deficiency in uterine leiomyosarcoma

 

Test Statistica

P-value

Vehicle vs caelyx 1.5 mg/kg

11.61

0.0007

Vehicle vs olaparib (6d) 150 mg/kg (3WKS)

0.17

0.7

Vehicle vs olaparib 150 mg/kg (6WKS)

0.017

0.9

Vehicle vs cisplatin 4 mg/kg

1.46

0.2

  1. aPairwise Log Rank Tests used to test the null hypothesis