Fig. 3

Cellular uptake of nanoparticles. (A) and (B) The expression and grayscale analysis of CD44 in NCM460, CT26, and CT26-Luc. (C) The cellular uptake of different ratios of HA and MPDA in CT26 cells and the statistical analysis of cellular efficiency in (D). (E) The cell uptake of nanoparticles with or without HA in CT26 cells and the statistical analysis of cellular efficiency in (F). (G) The inverted microscope image of uptake of C6@HA-MPDA along with time in CT26 cells. Data are presented as mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001