Fig. 8From: Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted deliveryIn vivo therapeutic efficacy of nanoparticles in a mouse model with early liver metastasis of colorectal cancer. (A) Therapeutic schedule. (B) The image of liver nodules of groups and the statistical analysis in (C). (D) The H&E strain of liver tissues. (E–F) Liver function index of serum (AST, ALT, and ALP). Data are presented as mean ± SD (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001Back to article page