Fig. 2From: CircZNF215 promotes tumor growth and metastasis through inactivation of the PTEN/AKT pathway in intrahepatic cholangiocarcinomacZNF215 facilitates cell proliferation, migration and invasion of iCCA cells in vitro. A and B Cell Counting Kit-8 (CCK-8) assays were performed to examine the role of cZNF215 in cell proliferation of iCCA cells upon knockdown and overexpression of cZNF215. C and D EdU cell proliferation assays of indicated iCCA cells. E-H Transwell migration and matrigel invasion assays of indicated iCCA cells. I-L Wound healing assays of indicated iCCA cells. Abbreviations: NC, normal control; OE, overexpression. Data represent means±SD of at least three independent experiments. Scale bars, 200 μmBack to article page