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Table 1 Clinical characteristics of 120 iCCA patients based on cZNF215 expression levels

From: CircZNF215 promotes tumor growth and metastasis through inactivation of the PTEN/AKT pathway in intrahepatic cholangiocarcinoma

Variables

Low cZNF215

(n = 60)

High cZNF215

(n = 60)

P value

Age, year, >60/≤60

27/33

26/34

0.854

Gender, male/female

28/32

32/28

0.465

Ascites, present/absent

3/57

10/50

0.075

Hepatolithiasis, present/absent

1/59

1/59

0.999

CA19-9, ≥260/<260

20/40

22/38

0.702

Tumor size (cm) >5/≤5

34/26

45/15

0.034

Tumor number, multiple/solitary

13/47

23/37

0.046

Differentiation, poor/well-moderate

44/16

46/14

0.673

MVI, present/absent

7/53

19/41

0.008

Lymph node, positive/negative

8/52

17/43

0.043

Cirrhosis, with/without

5/55

8/52

0.378

TNM stage, III/I- II

29/31

43/17

0.009

Chronic viral hepatitis B, present/absent

14/46

9/51

0.3538

  1. iCCA Intrahepatic cholangiocarcinoma, MVI Microvascular invasion, TNM Tumor-node-metastasis