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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: Integrated proteogenomic characterization reveals an imbalanced hepatocellular carcinoma microenvironment after incomplete radiofrequency ablation

Fig. 4

Enrichment analysis, altered subcellular localization and transcription factor analysis of DEPs. A-C GO, domain and KEGG enrichment analyses of the proteomics data. D Circus plot of enrichment analysis showing differences in proteomics profiles. Top 20 GO terms, pathways and domains in the outer track. The numbers and -log10 (p value) of DEPs in the second outer tracks: the length of each band represents the number of DEPs. The P value (smaller) corresponds to color intensity (redder). The third tracks show the ratio of DEPs. Blue and cyan represent the proportion of up- and downregulated proteins, respectively. The gridlines in the fourth tracks indicate the RichFactor values. E Subcellular localization of DEPs before iRFA and after iRFA. F: Protein number of the top 10 transcription factor families

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