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Retraction Note: Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis

The Original Article was published on 20 December 2018

Retraction Note: J Exp Clin Cancer Res 37, 320 (2018)

https://doi.org/10.1186/s13046-018-0993-y

The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding the data presented in some of the figures, specifically:

  • Figure 2C BGC-823 miR-NC images appear to overlap with Fig. 7C MKN45 LV-miR-IN + si GLS.

  • Figure 2D BGC-823 NC images appears highly similar to Fig. 5A MKN-45 miR-133a-3p IN+, HCQ+.

  • Figure 2E MKN-45 Invasion miR-133a-3p mimic image appears to overlap with BGC-823 Invasion miR-133a-3p mimic.

  • Figure 2E BGC-823 Migration miR-133a-3p mimic images appears to overlap with Fig. 7D BGC-823 Migration LV-miR-IN + BPTES.

  • Figure 2F miR-133a-3p mimic Day10 image appears highly similar to Fig. 5E circNRIP1 ov day1 in [1].

  • Figure 5D invasion miR-IN + si GABARAPL1 and miR-IN + HCQ images appear to overlap.

  • Figure 10F GLS LV-miR-133a-3p image appears to overlap with GDH LV-miR + HCQ + BPTES.

The Editor-in-Chief therefore no longer has confidence in the presented data.

Xing Zhang, Zheng Li, Zhe Xuan, Penghui Xu and Zekuan Xu agree to this retraction. Weizhi Wang, Zheng Chen, Sen Wang, Guangli Sun and Jianghao Xu have not responded to any correspondence from the editor or publisher about this retraction.

References

  1. Zhang X, Wang S, Wang H, et al. Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway. Mol Cancer. 2019;18:20. https://doi.org/10.1186/s12943-018-0935-5.

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Correspondence to Zekuan Xu.

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The online version of the original article can be found at https://doi.org/10.1186/s13046-018-0993-y.

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Zhang, X., Li, Z., Xuan, Z. et al. Retraction Note: Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis. J Exp Clin Cancer Res 43, 197 (2024). https://doi.org/10.1186/s13046-024-03123-7

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  • DOI: https://doi.org/10.1186/s13046-024-03123-7