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  1. Investigation of the expression of an intestinal stem cell marker in esophageal adenocarcinomas (EAC) with and without Barrett's Esophagus (BE), with respect to a cancer stem cell (CSC) hypothesis.

    Authors: Burkhard HA von Rahden, Stefan Kircher, Maria Lazariotou, Christoph Reiber, Luisa Stuermer, Christoph Otto, Christoph T Germer and Martin Grimm

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:23

    Content type: Research

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  2. Epidemiological studies propose that obesity increases the risk of several cancers, including melanoma. Obesity increases the expression of leptin, a multifunctional peptide produced predominantly by adipocyte...

    Authors: Fatemehsadat Amjadi, Shaghaygh Haghjooy Javanmard, Hamid Zarkesh-Esfahani, Majid Khazaei and Manijeh Narimani

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:21

    Content type: Research

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  3. Recently, miR-451 as a tumor suppressor has been reported in other studies. However, whether miR-451 can affect the sensitivity of non-small cell lung cancer (NSCLC) cells to cisplatin (DDP) remains unclear. T...

    Authors: Hai-Bo Bian, Xuan Pan, Jin-Song Yang, Zhao-Xia Wang and Wei De

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:20

    Content type: Research

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  4. Lung cancer is one of the most common human cancers and the leading cause of cancer death worldwide. The identification of lung cancer associated genes is essential for lung cancer diagnosis and treatment.

    Authors: Liangan Chen, Zhixin Liang, Qing Tian, Chunsun Li, Xiuqing Ma, Yu Zhang, Zhen Yang, Ping Wang and Yanqin Li

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:18

    Content type: Research

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  5. Bostrycin is a novel compound isolated from marine fungi that inhibits proliferation of many cancer cells. However, the inhibitory effect of bostrycin on lung cancers has not been reported. This study is to in...

    Authors: Wei-Sheng Chen, Jun-Na Hou, Yu-Biao Guo, Hui-Ling Yang, Can-Mao Xie, Yong-Cheng Lin and Zhi-Gang She

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:17

    Content type: Research

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  6. This retrospective analysis is focused on the efficacy and safety of radioimmunotherapy (RIT) with Zevalin® in nine patients with recurrent follicular lymphoma (FL) who were treated in a consolidation setting aft...

    Authors: Francesco Pisani, Carlo Ludovico Maini, Rosa Sciuto, Laura Dessanti, Mariella D'Andrea, Daniela Assisi and Maria Concetta Petti

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:16

    Content type: Case report

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  7. This study aimed to investigate the molecular structural relationship between cell adhesive molecule CD44 and Lewis y antigen, and determine the effects of Lewis y antigen on CD44-mediated adhesion and spreadi...

    Authors: Lili Gao, Limei Yan, Bei Lin, Jian Gao, Xiuyun Liang, Yanyan Wang, Juanjuan Liu, Shulan Zhang and Iwamori Masao

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:15

    Content type: Research

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  8. Cyclooxygenase-2 (COX-2) has recently been considered to promote lymphangiogenesis by up-regulating vascular endothelial growth factor-C (VEGF-C) in breast and lung cancer. However, the impact of COX-2 on lymp...

    Authors: Hong-Feng Gou, Xin-Chuan Chen, Jiang Zhu, Ming Jiang, Yu Yang, Dan Cao and Mei Hou

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:14

    Content type: Research

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  9. Streptococcus bovis (S. bovis) bacteria are associated with colorectal cancer and adenoma. S. bovis is currently named S. gallolyticus. 25 to 80% of patients with S. bovis/gallolyticus bacteremia have concomitant...

    Authors: Ahmed S Abdulamir, Rand R Hafidh and Fatimah Abu Bakar

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:11

    Content type: Review

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  10. To evaluate the therapeutic strategies commonly employed in the clinic for the management of brain metastases (BMs) and to correlate disease outcome with type of treatment and therapeutic resources available a...

    Authors: Alessandra Fabi, Alessandra Felici, Giulio Metro, Alessandra Mirri, Emilio Bria, Stefano Telera, Luca Moscetti, Michelangelo Russillo, Gaetano Lanzetta, Giovanni Mansueto, Andrea Pace, Marta Maschio, Antonello Vidiri, Isabella Sperduti, Francesco Cognetti and Carmine M Carapella

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:10

    Content type: Research

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  11. Stem cells are a relevant source of information about cellular differentiation, molecular processes and tissue homeostasis, but also one of the most putative biological tools to treat degenerative diseases. Th...

    Authors: Daniele Lodi, Tommaso Iannitti and Beniamino Palmieri

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:9

    Content type: Review

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  12. Hedgehog (Hh) signaling pathway is involved in regulation of many tissues development and oncogenesis. Recently, Hh signaling has been identified as a required functional pathway for leukemia stem cells(LSCs),...

    Authors: Bing Long, Huanling Zhu, Cuixia Zhu, Ting Liu and Wentong Meng

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:8

    Content type: Research

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  13. To implement a new cost efficacy internal Service for blood component irradiation, we carried out specific procedures and quality assurance reports using the linear accelerators (LINACs) of the Regina Elena In...

    Authors: Paola Pinnarò, Antonella Soriani, Daniela D'Alessio, Carolina Giordano, Maria Laura Foddai, Valentina Pinzi and Lidia Strigari

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:7

    Content type: Research

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  14. Vascular endothelial growth factor (VEGF) expression is up-regulated via a cyclooxygenase-2 (COX-2)-dependent mechanism in non-small cell lung cancer (NSCLC), but the specific signaling pathway involved is unc...

    Authors: Honghe Luo, Zhenguang Chen, Hui Jin, Mei Zhuang, Tao Wang, Chunhua Su, Yiyan Lei, Jianyong Zou and Beilong Zhong

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:6

    Content type: Research

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  15. SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various canc...

    Authors: Chan H Han, Yu-Jing Huang, Karen H Lu, Zhensheng Liu, Gordon B Mills, Qingyi Wei and Li-E Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:5

    Content type: Research

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  16. The best method to deliver intraperitoneal chemotherapy (IPC) for peritoneal carcinomatosis from ovarian cancer is not well defined. The aim of this study was to assess the ability of hyperthermia and adrenali...

    Authors: Olivier Facy, François Radais, Sylvain Ladoire, Delphine Delroeux, Hervé Tixier, François Ghiringhelli, Patrick Rat, Bruno Chauffert and Pablo Ortega-Deballon

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:4

    Content type: Research

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  17. An increasing body of evidence now implicates acetaldehyde as a major underlying factor for the carcinogenicity of alcoholic beverages and especially for oesophageal and oral cancer. Acetaldehyde associated wi...

    Authors: Dirk W Lachenmeier and Yulia B Monakhova

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:3

    Content type: Research

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  18. Cancer-testis antigens (CTAs) are suitable targets for cancer-specific immunotherapy. The aim of the study is to investigate the expression of CTAs in intrahepatic cholagiocarcinoma (IHCC) and evaluate their p...

    Authors: Jin-xue Zhou, Yin Li, Sun-xiao Chen and An-mei Deng

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:2

    Content type: Research

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  19. Telomerase plays an important role in cell proliferation and carcinogenesis and is believed to be a good target for anti-cancer drugs. Elimination of template function of telomerase RNA may repress the telomer...

    Authors: Yingying Lu, Junchao Gu, Dachuan Jin, Yanjing Gao and Mengbiao Yuan

    Citation: Journal of Experimental & Clinical Cancer Research 2011 30:1

    Content type: Research

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  20. Anticancer activities of several substituted naphthalimides (1H-benz[de]isoquinoline-1,3-diones) are well documented. Some of them have undergone Phase I-II clinical trials. Presently a series of ten N-(hydrox...

    Authors: Asama Mukherjee, Sushanta Dutta, Muthiah Shanmugavel, Dilip M Mondhe, Parduman R Sharma, Shashank K Singh, Ajit K Saxena and Utpal Sanyal

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:175

    Content type: Research

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  21. This study aimed to determine the miRNA profile in breast cancer stem cells (BCSCs) and to explore the functions of characteristic BCSC miRNAs.

    Authors: Jian-guo Sun, Rong-xia Liao, Jun Qiu, Jun-yu Jin, Xin-xin Wang, Yu-zhong Duan, Fang-lin Chen, Ping Hao, Qi-chao Xie, Zhi-xin Wang, De-zhi Li, Zheng-tang Chen and Shao-xiang Zhang

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:174

    Content type: Research

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  22. Primary and secondary drug resistance to imatinib and sunitinib in patients with gastrointestinal stromal tumors (GISTs) has led to a pressing need for new therapeutic strategies such as drug combinations. Mos...

    Authors: Maria Abbondanza Pantaleo, Giordano Nicoletti, Cristina Nanni, Chiara Gnocchi, Lorena Landuzzi, Carmelo Quarta, Stefano Boschi, Margherita Nannini, Monica Di Battista, Paolo Castellucci, Stefano Fanti, Pier Luigi Lollini, Elena Bellan, Mauro Castelli, Domenico Rubello and Guido Biasco

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:173

    Content type: Research

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  23. Specific gene expression is tightly regulated by various transcription factors. Osteopontin (OPN) is a phosphoprotein that mediates hepatocellular carcinoma (HCC) progression and metastasis. However, the mecha...

    Authors: Rong-Xin Chen, Yun-Hong Xia, Tong-Chun Xue and Sheng-Long Ye

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:172

    Content type: Research

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  24. The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues...

    Authors: Awatef Ben Jemaa, Yosra Bouraoui, Sataa Sallami, Ahmed Banasr, Nawfel Ben Rais, Latifa Ouertani, Yassin Nouira, Ali Horchani and Ridha Oueslati

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:171

    Content type: Research

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  25. The purpose of the study was to explore the anti-tumor effect of ultrasound -targeted microbubble destruction mediated herpes simplex virus thymidine kinase (HSV-TK) suicide gene system on mice hepatoma.

    Authors: Shiji Zhou, Shengwei Li, Zuojin Liu, Yong Tang, Zhigang Wang, Jianping Gong and Changan Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:170

    Content type: Research

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  26. The existence of cancer stem cells in hepatocellular carcinoma (HCC) has been verified by characterizing side population (SP) cells based on efflux of Hoechst 33342 dye from stem cells. Recent advances in micr...

    Authors: Ren Li, Niansong Qian, Kaishan Tao, Nan You, Xinchuan Wang and Kefeng Dou

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:169

    Content type: Research

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  27. The Open Archive Initiative (OAI) refers to a movement started around the '90s to guarantee free access to scientific information by removing the barriers to research results, especially those related to the e...

    Authors: Elisabetta Poltronieri, Ivana Truccolo, Corrado Di Benedetto, Mauro Castelli, Mauro Mazzocut and Gaetana Cognetti

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:168

    Content type: Research

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  28. ChromograninA in prostate carcinoma (PC) indicate NE differentiation. This tumour is more aggressive and resistant to hormone therapy.

    Authors: Marialuisa Appetecchia, Aurela Meçule, Giuseppe Pasimeni, Concetta V Iannucci, Piero De Carli, Roberto Baldelli, Agnese Barnabei, Giovanni Cigliana, Isabella Sperduti and Michele Gallucci

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:166

    Content type: Research

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  29. Imatinib, a selective tyrosine kinase inhibitor, has been used as a standard first-line therapy for irresectable and metastasized gastrointestinal stromal tumor (GIST) patients. Unfortunately, most patients re...

    Authors: Hoang Thanh Chi, Bui Thi Kim Ly, Takahiro Taguchi, Toshiki Watanabe and Yuko Sato

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:165

    Content type: Research

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  30. More data about TACE and pTACE seem necessary to better define the global treatment strategy for HCC. Aim of our analysis was to evaluate the role of TACE, either with lipiodol (traditional) or drug-eluting mi...

    Authors: Mario Scartozzi, Gianluca Svegliati Baroni, Luca Faloppi, Marzia Di Pietro Paolo, Chiara Pierantoni, Roberto Candelari, Rossana Berardi, Stefania Antognoli, Cinzia Mincarelli, Andrea Risaliti, Cristina Marmorale, Ettore Antico, Antonio Benedetti and Stefano Cascinu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:164

    Content type: Research

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  31. In spite of its establishment from the peripheral blood of a case with acute myeloid leukemia (AML)-M1, HPB-AML-I shows plastic adherence with spindle-like morphology. In addition, lipid droplets can be induce...

    Authors: Bambang Ardianto, Takeshi Sugimoto, Seiji Kawano, Shimpei Kasagi, Siti NA Jauharoh, Chiyo Kurimoto, Eiji Tatsumi, Keiko Morikawa, Shunichi Kumagai and Yoshitake Hayashi

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:163

    Content type: Research

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  32. Somatostatin prevents cell proliferation by inducing apoptosis. Downregulation of the XAF1 transcript may occur during the development of prostate cancer. It is interesting to evaluate the potential regulatory ef...

    Authors: Zhaoquan Xing, Zunlin Zhou, Rong Yu, Shuling Li, Chunde Li, Sten Nilsson and Zhaoxu Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:162

    Content type: Research

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  33. Pim-1 is a serine-threonine kinase which promotes early transformation, cell proliferation and cell survival during tumorigenesis. Several studies have demonstrated that Pim-1 kinase play a role in different c...

    Authors: Shengjie Guo, Xiaopeng Mao, Junxing Chen, Bin Huang, Chu Jin, Zhenbo Xu and Shaopeng Qiu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:161

    Content type: Research

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  34. Urinary bladder cancer is a common malignancy worldwide, and outcomes for patients with advanced bladder cancer remain poor. Antiproliferative factor (APF) is a potent glycopeptide inhibitor of epithelial cell...

    Authors: Hanief M Shahjee, Kristopher R Koch, Li Guo, Chen-Ou Zhang and Susan K Keay

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:160

    Content type: Research

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  35. Saikosaponin-a and -d, two naturally occurring compounds derived from Bupleurum radix, have been shown to exert anti-cancer activity in several cancer cell lines. However, the effect of combination of saikosap...

    Authors: Qiong Wang, Xue-lian Zheng, Lan Yang, Fang Shi, Lin-bo Gao, Ying-jia Zhong, Hong Sun, Fan He, Yong Lin and Xia Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:159

    Content type: Research

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  36. Chordoma was a typically slow-growing tumor. The therapeutic approach to chordoma had traditionally relied mainly on surgical therapy. And the main reason for therapeutic failure was resistance to chemotherapy...

    Authors: Zhengang Ji, Hua Long, Yunsheng Hu, Xiuchun Qiu, Xiang Chen, Zhao Li, Degang Fan, Baoan Ma and Qingyu Fan

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:158

    Content type: Research

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  37. The present report was designed to investigate the origins of elevated oxidative stress measured in cancer patients in our previous work related to a case-control study (17 cases, 43 controls) on oesophageal c...

    Authors: Stéphanie Lagadu, Mathilde Lechevrel, François Sichel, Jean Breton, Didier Pottier, Rémy Couderc, Fathi Moussa and Virginie Prevost

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:157

    Content type: Research

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  38. This study was conducted to investigate the expression of CXCR4 in portal vein tumor thrombus (PVTT) tissue and its possible role in the invasiveness of tumor thrombus cells.

    Authors: Nan Li, Weixing Guo, Jie Shi, Jie Xue, Huasheng Hu, Dong Xie, Mengchao Wu and Shuqun Cheng

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:156

    Content type: Research

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  39. Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described for different types of cancers and might be associated with cancer risk ...

    Authors: Ruixing Zhang, Rui Wang, Fengbin Zhang, Chensi Wu, Haiyan Fan, Yan Li, Cuiju Wang and Zhanjun Guo

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:155

    Content type: Research

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  40. Molecular therapies that target genetic abnormalities in leukemic cells and their affected signaling pathways have been emerging in pediatric acute lymphoblastic leukemia (ALL). Glycogen synthase kinase-3β (GS...

    Authors: Yanni Hu, Xiaoyan Gu, Ruiyan Li, Qing Luo and Youhua Xu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:154

    Content type: Research

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  41. Pleomorphic malignant fibrous histiocytoma (MFH) is one of the most frequent malignant soft tissue tumors in adults. Despite the considerable amount of research on MFH cell lines, their characterization at a m...

    Authors: Jun Nishio, Hiroshi Iwasaki, Kazuki Nabeshima, Masako Ishiguro, Teruto Isayama and Masatoshi Naito

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:153

    Content type: Research

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  42. Noninvasive and tissue-specific technologies of gene transfection would be valuable in clinical gene therapy. This present study was designed to determine whether it could enhance gene transfection in vivo by the...

    Authors: Zhi-Yi Chen, Kun Liang and Ri-Xiang Qiu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:152

    Content type: Research

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  43. MicroRNAs are important gene regulators that potentially play a profound role in tumorigenesis. Increasing evidence indicates that miR-145 is a tumor suppressor capable of inhibiting breast and colon cancer ce...

    Authors: Zhe Chen, Huazong Zeng, Yong Guo, Pei Liu, Hui Pan, Anmei Deng and Jian Hu

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:151

    Content type: Research

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  44. Glucocorticoid (GC) resistance is frequently seen in acute lymphoblastic leukemia of T-cell lineage (T-ALL). In this study we investigate the potential and mechanism of using rapamycin to restore the sensitivi...

    Authors: Ling Gu, Chenyan Zhou, Huajun Liu, Ju Gao, Qiang Li, Dezhi Mu and Zhigui Ma

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:150

    Content type: Research

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  45. Management of peritoneal dissemination is the most critical problem in gastric cancer. This study was performed to investigate the inhibitory effects of valproic acid (VPA) on a highly peritoneal-seeding cell ...

    Authors: Yasumichi Yagi, Sachio Fushida, Shinichi Harada, Jun Kinoshita, Isamu Makino, Katsunobu Oyama, Hidehiro Tajima, Hideto Fujita, Hiroyuki Takamura, Itasu Ninomiya, Takashi Fujimura, Tetsuo Ohta, Masakazu Yashiro and Kosei Hirakawa

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:149

    Content type: Research

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  46. Colloidal silver has been used as an antimicrobial and disinfectant agent. However, there is scarce information on its antitumor potential. The aim of this study was to determine if colloidal silver had cytoto...

    Authors: Moisés A Franco-Molina, Edgar Mendoza-Gamboa, Crystel A Sierra-Rivera, Ricardo A Gómez-Flores, Pablo Zapata-Benavides, Paloma Castillo-Tello, Juan Manuel Alcocer-González, Diana F Miranda-Hernández, Reyes S Tamez-Guerra and Cristina Rodríguez-Padilla

    Citation: Journal of Experimental & Clinical Cancer Research 2010 29:148

    Content type: Research

    Published on:

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