Owned by the Association for International Promotion & Study in Tumors (APSIT)
Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1
Preclinical toxicity of adaphostin has been related to oxidative stress. This study investigated the regulatory mechanism underlying adaphostin induction of heme oxygenase 1 (HMOX1) which plays a significant r...
Citation: Journal of Experimental & Clinical Cancer Research 2010 29:91