Skip to main content

Articles

Page 57 of 71

  1. Both BRCA1 and epidermal growth factor receptor (EGFR) play a critical role in ovarian cancer progression. However, the crosstalk between BRCA1 and EGFR signaling pathways in ovarian cancer remains largely unk...

    Authors: Da Li, Fang-Fang Bi, Ji-Min Cao, Chen Cao, Chun-Yan Li and Qing Yang
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:102
  2. Recently, leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1), a negative regulator of EGFR, was discovered is a novel agent for suppressing bladder cancer. The aim of this study was to investigate ...

    Authors: Lei Chang, Runlin Shi, Tao Yang, Fan Li, Guohao Li, Yonglian Guo, Bin Lang, Weimin Yang, Qianyuan Zhuang and Hua Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:101
  3. Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. The present treatment including surgery, chemotherapy and radiation, which have only 40% long-term cure rates, and usually cause tum...

    Authors: Xiao-Hong Tian, Wei-Jian Hou, Yan Fang, Jun Fan, Hao Tong, Shu-Ling Bai, Qu Chen, He Xu and Yan Li
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:100
  4. Paclitaxel, a widely used chemotherapeutic drug, can induce apoptosis in variety of cancer cells. A previous study has shown preferential toxicity of paclitaxel to FLCN-deficient kidney cancer cell line, UOK25...

    Authors: Qi Zhang, Shuhui Si, Sue Schoen, Jindong Chen, Xun-Bo Jin and Guan Wu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:99
  5. Mir-29 microRNA families are involved in regulation of various types of cancers. Although Mir-29 was shown to play an inhibitory role in tumorigenesis, the role of Mir-29 in breast cancer still remains obscure...

    Authors: Zhenglong Wu, Xiaona Huang, Xing Huang, Qiang Zou and Yujiang Guo
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:98
  6. Interleukin-27 signaling is mediated by the JAK-STAT pathway via activation of STAT1 and STAT3, which have tumor suppressive and oncogenic activities, respectively. Epithelial–mesenchymal transition (EMT) and ...

    Authors: Puja Kachroo, Mi-Heon Lee, Ling Zhang, Felicita Baratelli, Gina Lee, Minu K Srivastava, Gerald Wang, Tonya C Walser, Kostyantyn Krysan, Sherven Sharma, Steven M Dubinett and Jay M Lee
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:97
  7. Similar to protein-coding genes, miRNAs are also susceptible to epigenetic modulation. Although numerous miRNAs have been shown to be affected by DNA methylation, the regulatory mechanism of histone modificati...

    Authors: Xiaolan Liu, Xiaoyan Chen, Xinfang Yu, Yongguang Tao, Ann M Bode, Zigang Dong and Ya Cao
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:96
  8. Mutations in the DNA damage response (DDR) factors, breast cancer 1 (BRCA1) and BRCA2, sensitize tumor cells to poly(ADP-ribose) polymerase (PARP) inhibitors. The ataxia telangiectasia mutated (ATM) kinase is ...

    Authors: Maria Saveria Gilardini Montani, Andrea Prodosmo, Venturina Stagni, Dania Merli, Laura Monteonofrio, Veronica Gatti, Maria Pia Gentileschi, Daniela Barilà and Silvia Soddu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:95
  9. Although non muscle invasive bladder cancer (NMIBC) generally has a good long-term prognosis, up to 80% of patients will nevertheless experience local recurrence after the primary tumor resection. The search f...

    Authors: Valentina Casadio, Chiara Molinari, Daniele Calistri, Michela Tebaldi, Roberta Gunelli, Luigi Serra, Fabio Falcini, Chiara Zingaretti, Rosella Silvestrini, Dino Amadori and Wainer Zoli
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:94
  10. Antiangiogenic treatment may change the tumor microenvironment and hence influence the effect of conventional therapies. The potential of diffusion weighted magnetic resonance imaging (DW-MRI) and dynamic cont...

    Authors: Jon-Vidar Gaustad, Viktoria Pozdniakova, Tord Hompland, Trude G Simonsen and Einar K Rofstad
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:93
  11. Fluoropyrimidines, oxaliplatin, irinotecan and biologic therapies (Bevacizumab, Panitumumab, and Cetuximab) represent the backbone of metastatic colorectal cancer (CRC) treatment. The improvement in survival f...

    Authors: Giuseppe Tonini, Marco Imperatori, Bruno Vincenzi, Anna Maria Frezza and Daniele Santini
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:92
  12. One of the key oncogenic pathways involved in melanoma aggressiveness, development and progression is the RAS/BRAF/MEK pathway, whose alterations are found in most patients. These molecular anomalies are promi...

    Authors: Giovanni Sette, Katia Fecchi, Valentina Salvati, Fiorenza Lotti, Emanuela Pilozzi, Enrico Duranti, Mauro Biffoni, Alfredo Pagliuca, Daniela Martinetti, Lorenzo Memeo, Michele Milella, Ruggero De Maria and Adriana Eramo
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:91
  13. The principal Epstein–Barr virus (EBV) oncoprotein, latent membrane protein 1 (LMP1) is strongly associated with nasopharyngeal carcinoma (NPC), a prevalent cancer in China. The epidermal growth factor recepto...

    Authors: Yang Xu, Ying Shi, Qi Yuan, Xuli Liu, Bin Yan, Ling Chen, Yongguang Tao and Ya Cao
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:90
  14. The effectiveness of different breast cancer follow-up procedures to decrease breast cancer mortality are still an object of debate, even if intensive follow-up by imaging modalities is not recommended by inte...

    Authors: Isabella Sperduti, Patrizia Vici, Nicola Tinari, Teresa Gamucci, Michele De Tursi, Giada Cortese, Antonino Grassadonia, Stefano Iacobelli and Clara Natoli
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:89
  15. To investigate the potential dosimetric and clinical benefits of Deep Inspiration Breath-Hold (DIBH) technique during radiotherapy of breast cancer compared with Free Breathing (FB).

    Authors: Vicente Bruzzaniti, Armando Abate, Paola Pinnarò, Marco D’Andrea, Erminia Infusino, Valeria Landoni, Antonella Soriani, Carolina Giordano, Anna Maria Ferraro and Lidia Strigari
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:88
  16. To evaluate the prognostic role of TAMs in patients affected by non-muscle invasive bladder cancer (NMIBC), undergone Trans Urethral Resection of Bladder (TURB) and Bacillus Calmette-Guerin (BCG) therapy.

    Authors: Francesca Suriano, Daniele Santini, Giuseppe Perrone, Michela Amato, Bruno Vincenzi, Giuseppe Tonini, Andrea Onetti Muda, Sara Boggia, Maurizio Buscarini and Francesco Pantano
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:87
  17. Altered gene methylation, regulated by DNA methyltransferases (DNMT) 1, 3a and 3b, contributes to tumorigenesis. However, the role of DNMT in pancreatic ductal adenocarcinoma (PDAC) remains unknown.

    Authors: Jun Gao, Lihua Wang, Jinkang Xu, Jianming Zheng, Xiaohua Man, Hongyu Wu, Jin Jin, Kaixuan Wang, Huasheng Xiao, Shude Li and Zhaoshen Li
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:86
  18. The SNP309 polymorphism (T-G) in the promoter of MDM2 gene has been reported to be associated with enhanced MDM2 expression and tumor development. Studies investigating the association between MDM2 SNP309 poly...

    Authors: Qiliu Peng, Cuiju Mo, Aiping Qin, Xianjun Lao, Zhiping Chen, Jingzhe Sui, Junrong Wu, Limin Zhai, Shi Yang, Xue Qin and Shan Li
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:85
  19. According to the International Multidisciplinary Classification of Lung Adenocarcinoma (LAD) by International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society (IA...

    Authors: Jiayuan Huang, Haizhu Song, Biao Liu, Bo Yu, Rui Wang and Longbang Chen
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:84
  20. Mammalian target of rapamycin (mTOR) inhibitors are associated with dermatological adverse events. The chief aim of this study was to examine the relation between the signal transducer and activator of transcr...

    Authors: Kazuhiro Yamamoto, Atsushi Uda, Akira Mukai, Kazuhiko Yamashita, Manabu Kume, Hiroo Makimoto, Toshinori Bito, Chikako Nishigori, Takeshi Hirano and Midori Hirai
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:83
  21. Patients with advanced melanoma are faced with a poor prognosis and, until recently, limited treatment options. Ipilimumab, a novel immunotherapy that blocks cytotoxic T-lymphocyte-associated antigen-4, was th...

    Authors: Maresa Altomonte, Anna Maria Di Giacomo, Paola Queirolo, Paolo Antonio Ascierto, Francesco Spagnolo, Emilio Bajetta, Luana Calabrò, Riccardo Danielli, Francesco de Rosa, Michela Maur, Vanna Chiarion-Sileni, Pier Francesco Ferrucci, Diana Giannarelli, Alessandro Testori, Ruggero Ridolfi and Michele Maio
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:82
  22. The purpose of this study is to evaluate the radiation dose in patients undergoing liver angiographic procedure and verify the usefulness of different dose measurements to prevent deterministic effects. Gafchr...

    Authors: Daniela D’Alessio, Claudia Giliberti, Antonella Soriani, Livio Carpanese, Giuseppe Pizzi, Giulio Eugenio Vallati and Lidia Strigari
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:81
  23. Feasibility of whole breast hypofractionated radiotherapy schedules in breast conserving therapy is recognized however concerns remain about the role of the boost dose on the overall treatment’s potential toxi...

    Authors: Valeria Landoni, Carolina Giordano, Annelisa Marsella, Biancamaria Saracino, Maria Grazia Petrongari, Anna Maria Ferraro, Lidia Strigari and Paola Pinnarò
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:80
  24. Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway regulates multiple cellular processes such as cell proliferation, evasion from apoptosis, migration, glucose meta...

    Authors: Roberta Gonnella, Roberta Santarelli, Antonella Farina, Marisa Granato, Gabriella D’Orazi, Alberto Faggioni and Mara Cirone
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:79
  25. Three-dimensional (3D) minimally invasive video-assisted thyroidectomy (MIVAT) was carried out with a 4-mm, 3D 0-degree stereoscopic endoscope. The procedure was applied on 3 patients who underwent total thyro...

    Authors: Giuseppe Mercante, Paolo Battaglia, Valentina Manciocco, Giovanni Cristalli, Raul Pellini and Giuseppe Spriano
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:78
  26. Nucleobindin 2 (NUCB2) protein, a novel oncoprotein, is overexpressed in breast cancer. To date, there have been no published data regarding the role of NUCB2 protein expression in prostate cancer (PCa). There...

    Authors: Hongtuan Zhang, Can Qi, Andi Wang, Bing Yao, Liang Li, Yuzhuo Wang and Yong Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:77
  27. Metastasis is the major cause of cancer-related death in patients with gastric cancer, and aberrant expression of various microRNAs (miRNAs) is associated with cancer metastasis.

    Authors: Zishu Wang, Jin Wang, Yan Yang, Bo Hao, Rui Wang, Yumei Li and Qiong Wu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:76

    The Erratum to this article has been published in Journal of Experimental & Clinical Cancer Research 2014 33:18

  28. Polyploid giant cancer cells (PGCCs) contribute to solid tumor heterogeneity. This study investigated the relationships among PGCCs numbers, vasculogenic mimicry (VM) formation, and tumor grades in glioma.

    Authors: Yang Qu, Li Zhang, Zhe Rong, Tao He and Sai Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:75
  29. Osteosarcoma in dogs and humans share many similarities and the dog has been described as an excellent model to study this disease. The median survival in dogs has not improved in the last 25 years. Taurolidin...

    Authors: Kevin Marley, Stuart C Helfand, Jennifer Simpson, John E Mata, William G Tracewell, Lisa Brownlee, Shay Bracha and Bernard Séguin
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:74
  30. Cutaneous melanoma is a malignant neoplasm with a constantly increasing incidence, the prognosis of which is largely dependent on early diagnosis. The appropriateness of requests for ultrasound (US) tests duri...

    Authors: Francesco M Solivetti, Fulvia Elia, Antonino Guerrisi, Flora Desiderio, Maria Giulia Santaguida, Isabella Sperduti, Claudia Cavallotti and Aldo Di Carlo
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:73
  31. Mutations of the p53 oncosuppressor gene are amongst the most frequent aberration seen in human cancer. Some mutant (mt) p53 proteins are prone to loss of Zn(II) ion that is bound to the wild-type (wt) core, p...

    Authors: Alessia Garufi, Daniela Trisciuoglio, Manuela Porru, Carlo Leonetti, Antonella Stoppacciaro, Valerio D’Orazi, Maria Laura Avantaggiati, Alessandra Crispini, Daniela Pucci and Gabriella D’Orazi
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:72
  32. The diagnostic and prognostic value of microRNA (miRNA) expression aberrations in pancreatic ductal adenocarcinoma (PDAC) has been studied extensively in recent years. However, differences in measurement platf...

    Authors: Ming-Zhe Ma, Xiang Kong, Ming-Zhe Weng, Kun Cheng, Wei Gong, Zhi-Wei Quan and Cheng-Hong Peng
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:71
  33. Inflammatory breast cancer (IBC) is the most metastatic variant of breast cancer with the poorest survival in all types of breast cancer patients and presently therapeutic targets for IBC are very limited. Enh...

    Authors: Zhaomei Mu, Hua Li, Sandra V Fernandez, Katherine R Alpaugh, Rugang Zhang and Massimo Cristofanilli
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:70
  34. Recently, we reported an association of a novel cancer testis (CT) antigen, sperm-associated antigen 9 (SPAG9) expression in breast cancer clinical samples, indicating its potential role in carcinogenesis. Aro...

    Authors: Abhilasha Sinha, Sumit Agarwal, Deepak Parashar, Archana Verma, Shikha Saini, Nirmala Jagadish, Abdul S Ansari, Nirmal K Lohiya and Anil Suri
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:69
  35. Quadruplexes DNA are present in telomeric DNA as well as in several cancer-related gene promoters and hence affect gene expression and subsequent biological processes. The conformations of G4 provide selective...

    Authors: Sara Iachettini, Malcolm FG Stevens, Mark Frigerio, Marc G Hummersone, Ian Hutchinson, Thomas P Garner, Mark S Searle, David W Wilson, Manoj Munde, Rupesh Nanjunda, Carmen D’Angelo, Pasquale Zizza, Angela Rizzo, Chiara Cingolani, Federica De Cicco, Manuela Porru…
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:68
  36. The role of second-line therapy in gastric cancer patients mostly stemmed from clinical trials with monochemotherapy carried out in Asian countries. Nevertheless, these results cannot be broadly generalized as...

    Authors: Marcello Maugeri-Saccà, Laura Pizzuti, Domenico Sergi, Maddalena Barba, Franca Belli, Silvia Ileana Fattoruso, Diana Giannarelli, Antonella Amodio, Sara Boggia, Patrizia Vici and Luigi Di Lauro
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:67
  37. L1 cell adhesion molecule (L1CAM) and epithelial cell adhesion molecule (EPCAM) have been implicated in the development and progression of gastric cancer. The present study investigated the clinical significan...

    Authors: Yuan-Yu Wang, Li Li, Zhong-Sheng Zhao, Yong-Xiang Wang, Zai-Yuan Ye and Hou-Quan Tao
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:66
  38. To detect genes correlated with hepatocellular carcinoma (HCC), we developed a triple combination array consisting of methylation array, gene expression array and single nucleotide polymorphism (SNP) array ana...

    Authors: Yoshikuni Inokawa, Shuji Nomoto, Mitsuhiro Hishida, Masamichi Hayashi, Mitsuro Kanda, Yoko Nishikawa, Shin Takeda, Hiroyuki Sugimoto, Tsutomu Fujii, Suguru Yamada and Yasuhiro Kodera
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:65
  39. Among the numerous genetic defects associated with hepatocarcinogenesis, telomere abnormalities appear to play a role both in tumor promotion and maintenance. Telomeres, the chromosome extremities, are protect...

    Authors: Manale El Idrissi, Valérie Hervieu, Philippe Merle, Franck Mortreux and Eric Wattel
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:64
  40. Cellfood™ (CF) is a nutritional supplement containing deuterium sulphate, minerals, amino acids, and enzymes, with well documented antioxidant properties. Its organic and inorganic components are extracted fro...

    Authors: Simona Catalani, Valentina Carbonaro, Francesco Palma, Marselina Arshakyan, Rossella Galati, Barbara Nuvoli, Serafina Battistelli, Franco Canestrari and Serena Benedetti
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:63
  41. Increased motility and invasiveness of cancer cells are reminiscent of the epithelial-mesenchymal transition (EMT), which occurs during cancer progression and metastasis. Recent studies have indicated the expr...

    Authors: Masanobu Tsubaki, Makiko Komai, Shin-ichiro Fujimoto, Tatsuki Itoh, Motohiro Imano, Kotaro Sakamoto, Hirotaka Shimaoka, Tomoya Takeda, Naoki Ogawa, Kenji Mashimo, Daiichiro Fujiwara, Junji Mukai, Katsuhiko Sakaguchi, Takao Satou and Shozo Nishida
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:62
  42. There is no consensus regarding the secondary cytoreduction surgery (CRS) in recurrent ovarian cancer patients. The present study aims to determine the value of secondary CRS and the eligible subgroup for this...

    Authors: Xia Xu, Xiaoxiang Chen, Zhiqin Dai, Fei Deng, Junwei Qu and Jing Ni
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:61
  43. The deleted in liver cancer 1 (DLC1) and plasminogen activator inhibitor 1 (PAI-1) are known to be closely associated with tumor growth and metastasis in several kinds of human tumors. The aim of this study wa...

    Authors: Fang Ren, Huirong Shi, Gong Zhang and Ruitao Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:60
  44. To date, no prognostic microRNAs (miRNAs) for isocitrate dehydrogenase 1 (IDH1) wild-type glioblastoma multiformes (GBM) have been reported. The aim of the present study was to identify a miRNA signature of pr...

    Authors: Zheng Wang, Zhaoshi Bao, Wei Yan, Gan You, Yinyan Wang, Xuejun Li and Wei Zhang
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:59
  45. An External Quality Assessment (EQA) program was developed to investigate the state of the art of HER2 immunohistochemical determination in breast cancer (BC) in 16 Pathology Departments in the Lazio Region (I...

    Authors: Irene Terrenato, Vincenzo Arena, Sara Pizzamiglio, Ilaria Pennacchia, Letizia Perracchio, Simonetta Buglioni, Cristiana Ercolani, Francesca Sperati, Leopoldo Costarelli, Elena Bonanno, Daniela Baldini, Silvia Candia, Anna Crescenzi, Antonella Dal Mas, Claudio Di Cristofano, Vito Gomes…
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:58
  46. Renal cell carcinoma (RCC), the most common malignancy of the kidney, is refractory to standard therapy and has an incidence that continues to rise. Screening of plant extracts in search of new agents to treat...

    Authors: Richard T Williams, Alice L Yu, Mitchell B Diccianni, Emmanuel A Theodorakis and Ayse Batova
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:57

    The Erratum to this article has been published in Journal of Experimental & Clinical Cancer Research 2014 33:95

  47. Nucleobindin 2 (NUCB2) abnormal expression has been reported in gastric cancer and breast cancer. However, the role of NUCB2 in prostate cancer (PCa) remains unclear. The aim of the present study was to invest...

    Authors: Hongtuan Zhang, Can Qi, Liang Li, Fei Luo and Yong Xu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:56
  48. Neuroepithelial Transforming Gene 1 (NET1) is a well characterised oncoprotein and a proven marker of an aggressive phenotype in a number of cancers, including gastric adenocarcinoma. We aimed to investigate w...

    Authors: Conor Lahiff, Eoin Cotter, Rory Casey, Peter Doran, Graham Pidgeon, John Reynolds, Padraic MacMathuna and David Murray
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:55
  49. The prognostic value of metastasis-associated gene 1 (MTA1) in nasopharyngeal carcinoma (NPC) has been suggested. However, there is still no direct evidence that MTA1 promotes NPC growth in vivo. In this study...

    Authors: Qingcui Song, Hong Zhang, Min Wang, Wen Song, Min Ying, Yuan Fang, Yiyi Li, Yilan Chao and Xiaoxia Zhu
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:54
  50. The association between striking life events, an important stress and acute anxiety disorder, and the occurrence of primary breast cancer is unclear. The current meta-analysis was designed to assess the relati...

    Authors: Yan Lin, Changjun Wang, Ying Zhong, Xin Huang, Li Peng, Guangliang Shan, Ke Wang and Qiang Sun
    Citation: Journal of Experimental & Clinical Cancer Research 2013 32:53

Annual Journal Metrics

  • 2022 Citation Impact
    11.3 - 2-year Impact Factor
    11.5 - 5-year Impact Factor
    1.870 - SNIP (Source Normalized Impact per Paper)
    2.413 - SJR (SCImago Journal Rank)

    2022 Speed
    5 days submission to first editorial decision for all manuscripts (Median)
    97 days submission to accept (Median)

    2022 Usage 
    2,694,347 downloads
    4,666 Altmetric mentions