Skip to main content

Advertisement

Articles

Page 46 of 47

  1. Sirolimus is recently reported to have antitumour effects on a large variety of cancers. The present study was performed to investigate sirolimus's ability to inhibit growth in T24 bladder cancer cells.

    Authors: Rosario Pinto-Leite, Pedro Botelho, Eufemia Ribeiro, Paula A Oliveira and Lucios Santos

    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:3

    Content type: Research

    Published on:

  2. This study aimed to analyze three-dimensional (3D) dosimetric data of conventional two-dimensional (2D) palliative spinal bone irradiation using different reference points and treatment plans with respect to t...

    Authors: Fundagul Andic, Sule Baz Cifci, Yasemin Ors, Umar Niang, Ahmet Dirier and Mustafa Adli

    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:2

    Content type: Research

    Published on:

  3. To study the efficacy of whole brain radiotherapy (WBRT) with radiosensitizer in comparison with WBRT alone for patients with brain metastases in terms of overall survival, disease progression, response to tre...

    Authors: Gustavo Arruda Viani, Gustavo Borges Manta, Ellen Carrara Fonseca, Ligia Issa De fendi, Sergio Luis Afonso and Eduardo Jose Stefano

    Citation: Journal of Experimental & Clinical Cancer Research 2009 28:1

    Content type: Research

    Published on:

  4. Microsatellite instability (MSI) at tri- or tetranucleotide repeat markers (elevated microsatellite alterations at selected tetranucleotide repeat, EMAST) has been recently described. But, the underlying genet...

    Authors: Yoo Duk Choi, Jin Choi, Jo Heon Kim, Ji Shin Lee, Jae Hyuk Lee, Chan Choi, Ho Sun Choi, Min Cheol Lee, Chang Soo Park, Sang Woo Juhng and Jong Hee Nam

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:88

    Content type: Research

    Published on:

  5. To investigate, in vitro, the regulatory effects of tumor-suppressing gene PTEN on mTOR (mammalian target of rapamycin) signaling pathway, the effects of transfected PTEN and rapamycin on the growth inhibition, a...

    Authors: Zhi Y Cheng, Xiao L Guo, Xiao Y Yang, Zhi Y Niu, Shi H Li, Su Y Wang, Hao Chen and Ling Pan

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:87

    Content type: Research

    Published on:

  6. The antiangiogenic agent cilengitide disrupts integrin binding to the extracellular matrix leading to apoptosis of activated endothelial cells. Integrins are also widely expressed in malignant glioma and integ...

    Authors: Leticia Oliveira-Ferrer, Jessica Hauschild, Walter Fiedler, Carsten Bokemeyer, Johannes Nippgen, Ilhan Celik and Gunter Schuch

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:86

    Content type: Research

    Published on:

  7. Gliomas represent the most frequent neoplasm of the central nervous system. Unfortunately, surgical cure of it is practically impossible and their clinical course is primarily determined by the biological beha...

    Authors: Mingyu Zhang, Tao Song, Liang Yang, Ruokun Chen, Lei Wu, Zhuanyi Yang and Jiasheng Fang

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:85

    Content type: Research

    Published on:

  8. HPV vaccine is an exciting promise of the preventive medicine. Although HPV-immunization programs still reveal a number of unanswered questions, they represent a novel opportunity for primary prevention agains...

    Authors: Luciano Mariani and Sonia Pagliusi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:84

    Content type: Editorial

    Published on:

  9. Lipocalin 2, an iron binding protein, is abnormally expressed in some malignant human cancers and may play an important role in tumor metastasis. However, the roles of lipocalin 2 in breast cancer formation an...

    Authors: Han Shi, Yuchao Gu, Jing Yang, Liang Xu, Wenyi Mi and Wengong Yu

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:83

    Content type: Research

    Published on:

  10. Disseminated soft tissue sarcoma still represents a therapeutic dilemma because effective cytostatics are missing. Therefore we tested TRAIL and Tarolidine (TRD), two substances with apoptogenic properties on ...

    Authors: Adrien Daigeler, Christina Brenzel, Daniel Bulut, Anne Geisler, Christoph Hilgert, Marcus Lehnhardt, Hans U Steinau, Annegret Flier, Lars Steinstraesser, Ludger Klein-Hitpass, Ulrich Mittelkötter, Waldemar Uhl and Ansgar M Chromik

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:82

    Content type: Research

    Published on:

  11. Treatment of cancer patients with anthracycline antibiotic doxorubicin (DOX) may be complicated by development of acute and chronic congestive heart failure (CHF), malignant arrhythmias and death. The aim of t...

    Authors: Elmir Omerovic, Malin Linbom, Truls Råmunddal, Ann Lindgård, Ingrid Undeland, Ann-Sofie Sandberg and Bassam Soussi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:81

    Content type: Research

    Published on:

  12. Prophylactic cranial irradiation (PCI) has been demonstrated to reduce or delay the incidence of brain metastases (BM) in locally advanced non-small cell lung carcinoma (LA-NSCLC) patients with various prognos...

    Authors: Ali Aydin Yavuz, Erkan Topkan, Cem Onal and Melek Nur Yavuz

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:80

    Content type: Research

    Published on:

  13. In sentinel node (SN) detection for cases of early gastric cancer, the submucosal dye injection method appears to be more reasonable than the subserosal injection. To compare the two injection methods, we have...

    Authors: Yoshihisa Yaguchi, Takashi Ichikura, Satoshi Ono, Hironori Tsujimoto, Hidekazu Sugasawa, Naoko Sakamoto, Yusuke Matsumoto, Kazumichi Yoshida, Shigeru Kosuda and Kazuo Hase

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:79

    Content type: Research

    Published on:

  14. Since successful treatment of superficial bladder cancer with BCG requires proper induction of Th1 immunity, we have developed a rBCG-S1PT strain that induced a stronger cellular immune response than BCG. This...

    Authors: Daher C Chade, Ricardo C Borra, Ivan P Nascimento, Fabiola E Villanova, Luciana CC Leite, Enrico Andrade, Miguel Srougi, Kátia L Ramos and Priscila M Andrade

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:78

    Content type: Research

    Published on:

  15. IQGAP1 is a scaffolding protein and overexpressed in many human tumors, including ovarian cancer. However, the contribution of IQGAP1 to invasive properties of ovarian cancer cells remains unknown. Here, we in...

    Authors: Pei-Xin Dong, Nan Jia, Zhu-Jie Xu, Ying-Tao Liu, Da-Jin Li and You-Ji Feng

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:77

    Content type: Research

    Published on:

  16. Chemoresistance is a serious problem in pancreatic cancer, but the mechanism of resistance and strategies against the resistance have not been elucidated. We examined the potential of the phosphatidylinositol ...

    Authors: Masao Fujiwara, Kunihiko Izuishi, Takanori Sano, Mohammad Akram Hossain, Shoji Kimura, Tsutomu Masaki and Yasuyuki Suzuki

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:76

    Content type: Research

    Published on:

  17. Oncogenetic counselling is seldom followed through, even when individuals are eligible according to the test criteria. The basic variables which influence the decision to undergo the genetic counselling proces...

    Authors: Anita Caruso, Cristina Vigna, Gabriella Maggi, Fabio Massimo Sega, Francesco Cognetti and Antonella Savarese

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:75

    Content type: Research

    Published on:

  18. The aim of this study is to evaluate the prognostic factors of overall survival (OS) after haematopoietic stem cell transplant (HSCT) in acute lymphoblastic leukaemia (ALL) patients using accelerated failure t...

    Authors: Kourosh Sayehmiri, Mohammad R Eshraghian, Kazem Mohammad, Kamran Alimoghaddam, Abbas Rahimi Foroushani, Hojjat Zeraati, Banafsheh Golestan and Ardeshir Ghavamzadeh

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:74

    Content type: Research

    Published on:

  19. The function of promyelocytic leukemia (PML) bodies is not well known but plays an important role in controlling cell proliferation, apoptosis and senescence. This study was undertaken to analyze the clinical ...

    Authors: Toshihiro Matsuo, Takashi Sugita, Shoji Shimose, Tadahiko Kubo, Masataka Ishikawa, Yuji Yasunaga and Mitsuo Ochi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:73

    Content type: Research

    Published on:

  20. RNA interference (RNAi) has been successfully applied in suppression of hepatic cancer genes. In hepatocelluar carcinoma cell, one methionine adenosyltransferase (MAT) isozyme, MATII was found to have two cata...

    Authors: Qun Wang, Quan-yan Liu, Zhi-Su Liu, Qun Qian, Quan Sun and Ding-yu Pan

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:72

    Content type: Research

    Published on:

  21. The understanding of cutaneous pigmentation biology is relevant from the biologic and clinical point of view. The binding of α-melanocortin and its specific receptor, on the plasma membrane of melanin synthesi...

    Authors: Stefania Miccadei, Barbara Pascucci, Mauro Picardo, Pier Giorgio Natali and Donato Civitareale

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:71

    Content type: Research

    Published on:

  22. Tumours are classified according to the most differentiated cells with the exception of carcinomas where a few tumour cells show neuroendocrine differentiation. In this case these cells are regarded as rediffe...

    Authors: Helge L Waldum, Arne K Sandvik, Eiliv Brenna, Reidar Fossmark, Gunnar Qvigstad and Jun Soga

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:70

    Content type: Review

    Published on:

  23. The helix-loop-helix transcription factor Id-1 (an inhibitor of differentiation and DNA binding) plays a role in development and progression of many tumours. Id-1 is known to exert its effects on the epidermal...

    Authors: Ibrahim Meteoglu, Nezih Meydan and Muhan Erkus

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:69

    Content type: Research

    Published on:

  24. Cisplatin, a platinum based anticancer drug has played a vital role in the treatment of cancers by chemical agents, but in view of the serious toxicity including nephrotoxicity of cisplatin, various other plat...

    Authors: Shipra Pal, Arpita Sengupta Sadhu, Swarup Patra and Kalyan K Mukherjea

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:68

    Content type: Research

    Published on:

  25. The aim of this retrospective study was to assess the results concerning the regional and systemic toxicity and complications in 242 chemo-hyperthermal treatments (HILPs) for lower limb melanoma.

    Authors: Marcello Pace, Riccardo Gattai, Maria Matteini, Erminia Macera Mascitelli and Paolo Bechi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:67

    Content type: Research

    Published on:

  26. The goal of this study was to determine the effects of a selective Cyclooxygenase (COX)-2 inhibitor on the inhibition of tumor growth and pulmonary metastasis in a Lewis Lung Carcinoma (LLC) animal model.

    Authors: Won Park, Young Taek Oh, Jae Ho Han and Hongryull Pyo

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:66

    Content type: Research

    Published on:

  27. Metatypical cell carcinoma can be considered as a new entity of skin cancer, being an intermediate typology between basal cell carcinomas and squamous cell carcinomas. The behaviour of the metatypical cell car...

    Authors: Mauro Tarallo, Emanuele Cigna, Riccardo Frati, Sergio Delfino, Daniele Innocenzi, Umberto Fama, Annamaria Corbianco and Nicolò Scuderi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:65

    Content type: Review

    Published on:

  28. Thymidine phosphorylase (TP) is identical with platelet-derived endothelial cell growth factor (PD-ECGF) which promotes angiogenesis. The aim of this study was to evaluate the cytosol activity of TP in tumor s...

    Authors: Elżbieta Miszczak-Zaborska, Robert Kubiak, Andrzej Bieńkiewicz and Jacek Bartkowiak

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:64

    Content type: Research

    Published on:

  29. Interferon-γ-inducible protein 10 (IP-10) is a potent inhibitor of tumor angiogenesis. It has been reported that the antiangiogenic therapy combined with chemotherapy has synergistic effects.

    Authors: Kai Mei, Lian Wang, Ling Tian, Jingrui Yu, Zhixuan Zhang and Yuquan Wei

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:63

    Content type: Research

    Published on:

  30. Endostatin and anastellin, fragments of collagen type XVIII and fibronectin, respectively, belong to a family of endogenous inhibitors of angiogenesis which inhibit tumor growth and metastasis in a number of m...

    Authors: David M Neskey, Anthony Ambesi, Kevin M Pumiglia and Paula J McKeown-Longo

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:61

    Content type: Research

    Published on:

  31. Sticker's sarcoma (also known as transmissible venereal tumor) is a horizontally transmitted neoplasm of the dog, that is passed with coitus. It is a locally aggressive tumor with a low tendency to metastatic ...

    Authors: Enrico P Spugnini, Ivan Dotsinsky, Nikolay Mudrov, Gennaro Citro, Alfredo D'Avino and Alfonso Baldi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:58

    Content type: Research

    Published on:

  32. We explore the use of a clinical orthovoltage X-ray treatment unit as a small-animal radiation therapy system in a tumoral model of cervical cancer.

    Authors: Luis-Alberto Medina, Blanca-Ivone Herrera-Penilla, Mario-Alberto Castro-Morales, Patricia García-López, Rafael Jurado, Enrique Pérez-Cárdenas, José Chanona-Vilchis and María-Ester Brandan

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:57

    Content type: Research

    Published on:

  33. Treatment failure after radiotherapy of head and neck squamous cell carcinoma (HNSCC) could be a significant problem. Our objective is to sensitize SCCVII cells to ionizing radiation in vitro and in vivo through ...

    Authors: Jian Zou, Xiaoming Qiao, Huiping Ye, Yuqiong Yang, Xuelian Zheng, Houyu Zhao and Shixi Liu

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:56

    Content type: Research

    Published on:

  34. The RON receptor tyrosine kinase regulates epithelial cell homeostasis and tumorigenesis by transducing multiple signals through its functional domains. The present study was to determine the significance of t...

    Authors: Yi Lu, Hang-Ping Yao and Ming-Hai Wang

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:55

    Content type: Research

    Published on:

  35. The activity of dihydropyrimidine dehydrogenase (DPD), the key enzyme of pyrimidine catabolism, is thought to be an important determinant for the occurrence of severe toxic reactions to 5-fluorouracil (5-FU), ...

    Authors: Ursula Amstutz, Simone Farese, Stefan Aebi and Carlo R Largiadèr

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:54

    Content type: Research

    Published on:

  36. Clear cell renal cell carcinoma (ccRCC) is the most frequently encountered tumor in the adult kidney. Many factors are known to take part in the development and progression of this tumor. Nuclear factor kappa ...

    Authors: Ibrahim Meteoglu, Ibrahim H Erdogdu, Nezih Meydan, Muhan Erkus and Sabri Barutca

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:53

    Content type: Research

    Published on:

  37. PET (Positron Emission Tomography) is a nuclear medicine imaging method, frequently used in oncology during the last years. It is a non-invasive technique that provides quantitative in vivo assessment of physi...

    Authors: Evelina Miele, Gian Paolo Spinelli, Federica Tomao, Angelo Zullo, Filippo De Marinis, Giulia Pasciuti, Luigi Rossi, Federica Zoratto and Silverio Tomao

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:52

    Content type: Review

    Published on:

  38. p27Kip1 plays a major role as a negative regulator of the cell cycle. The regulation of p27Kip1 degradation is mediated by its specific ubiquitin ligase subunits S-phase kinase protein (Skp) 2 and cyclin-dependen...

    Authors: Zheng Liu, Qiang Fu, Jiaju Lv, Facheng Wang and Kejia Ding

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:51

    Content type: Research

    Published on:

  39. CD147 plays a critical role in the invasive and metastatic activity of hepatocellular carcinoma (HCC) cells by stimulating the surrounding fibroblasts to express matrix metalloproteinases (MMPs). Tumor cells a...

    Authors: Ai-Rong Qian, Wei Zhang, Jian-Ping Cao, Peng-Fei Yang, Xiang Gao, Zhe Wang, Hui-Yun Xu, Yuan-Yuan Weng and Peng Shang

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:50

    Content type: Research

    Published on:

  40. Genetic polymorphisms of DNA repair enzymes may lead to genetic instability and colorectal cancer carcinogenesis. Our objective was to measure the interactions between polymorphisms of repair genes and tobacco...

    Authors: Mayumi Kasahara, Kayo Osawa, Kana Yoshida, Aiko Miyaishi, Yasunori Osawa, Natsuko Inoue, Akimitsu Tsutou, Yoshiki Tabuchi, Kenichi Tanaka, Masahiro Yamamoto, Etsuji Shimada and Juro Takahashi

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:49

    Content type: Research

    Published on:

  41. Second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI (Smac/DIABLO) is a proapoptogenic mitochondrial protein that is released to the cytosol in response to...

    Authors: Gustavo Martinez-Ruiz, Vilma Maldonado, Gisela Ceballos-Cancino, Juan P Reyes Grajeda and Jorge Melendez-Zajgla

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:48

    Content type: Review

    Published on:

  42. Metastasis in breast cancer is a vital concern in treatment because most women with primary breast cancer have micrometastases to distant sites at diagnosis. As a member of the inhibitor of apoptosis protein (...

    Authors: Xing-Chen Peng, Li Yang, Li-Ping Yang, Yong-Qiu Mao, Han-Shuo Yang, Ji-Yan Liu, Dong-Mei Zhang, li-Juan Chen and Yu-Quan Wei

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:46

    Content type: Research

    Published on:

  43. Lung cancer is the commonest cause of cancer death in developed countries. Adenocarcinoma is becoming the most common form of lung cancer. Cigarette smoking is the main risk factor for lung cancer. Long-term c...

    Authors: David Stav, Ilan Bar and Judith Sandbank

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:45

    Content type: Research

    Published on:

  44. Reactive oxygen species (ROS) are intricately involved in tumor progression through effects on proliferation, apoptosis and metastasis. But how ROS works is not well understood. In previous study, we found PUM...

    Authors: Xinying Wang, Jing Wang, Shiyong Lin, Yan Geng, Jide Wang and Bo Jiang

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:44

    Content type: Research

    Published on:

  45. Valid interview data is critical to the final results of the study. The purpose of this study was to investigate the reliability of epidemiological data obtained in non-smoking female lung cancer case-control ...

    Authors: Desheng Huang, Peng Guan, Hailong Shi, Qincheng He and Baosen Zhou

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:43

    Content type: Research

    Published on:

  46. To investigate the feasibility of gene therapy in treating Epstein-Barr virus (EBV)-associated cancer by employing the suicide gene, herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV), which uses t...

    Authors: Yang Lifang, Tang Min, Ai Midan and Cao Ya

    Citation: Journal of Experimental & Clinical Cancer Research 2008 27:42

    Content type: Research

    Published on:

Annual Journal Metrics

Advertisement